Induction of protective immunity by multiantigenic DNA vaccine delivered in attenuated Salmonella typhimurium against Toxoplasma gondii infection in mice

2009 ◽  
Vol 166 (3-4) ◽  
pp. 220-227 ◽  
Author(s):  
Daofeng Qu ◽  
Haijie Yu ◽  
Suhua Wang ◽  
Weiming Cai ◽  
Aifang Du
2005 ◽  
Vol 73 (1) ◽  
pp. 617-621 ◽  
Author(s):  
Michelle N. Kelly ◽  
Jay K. Kolls ◽  
Kyle Happel ◽  
Joseph D. Schwartzman ◽  
Paul Schwarzenberger ◽  
...  

ABSTRACT We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R−/− mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear leukocytes to infected sites during early infection.


2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Samantha J. Batista ◽  
Katherine M. Still ◽  
David Johanson ◽  
Jeremy A. Thompson ◽  
Carleigh A. OʼBrien ◽  
...  

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