Protective immunity induced by a DNA vaccine cocktail expressing TgSAG1, TgROP2, and the genetic adjuvant HBsAg against Toxoplasma gondii infection

2020 ◽  
Vol 147 ◽  
pp. 104441
Author(s):  
Hui Sun ◽  
Jin Li ◽  
Ting Xiao ◽  
Xiao-Dan Huang ◽  
Long-jiang Wang ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Dna Vaccine ◽  
Protective Immunity ◽  
Toxoplasma Gondii Infection

scholarly journals Interleukin-17/Interleukin-17 Receptor-Mediated Signaling Is Important for Generation of an Optimal Polymorphonuclear Response against Toxoplasma gondii Infection

2005 ◽  
Vol 73 (1) ◽  
pp. 617-621 ◽  
Author(s):  
Michelle N. Kelly ◽  
Jay K. Kolls ◽  
Kyle Happel ◽  
Joseph D. Schwartzman ◽  
Paul Schwarzenberger ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Adaptive Immunity ◽  
Protective Immunity ◽  
Polymorphonuclear Leukocytes ◽  
Early Infection ◽  
Interleukin 17 ◽  
Toxoplasma Gondii Infection ◽  
Knockout Animals

ABSTRACT We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R−/− mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear leukocytes to infected sites during early infection.

scholarly journals Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Samantha J. Batista ◽  
Katherine M. Still ◽  
David Johanson ◽  
Jeremy A. Thompson ◽  
Carleigh A. OʼBrien ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Protective Immunity ◽  
Toxoplasma Gondii Infection

Protective immunity induced by a DNA vaccine-encoding Toxoplasma gondii microneme protein 11 against acute toxoplasmosis in BALB/c mice

2013 ◽  
Vol 112 (8) ◽  
pp. 2871-2877 ◽  
Author(s):  
Qing Tao ◽  
Rui Fang ◽  
Weichao Zhang ◽  
Yifan Wang ◽  
Jianxi Cheng ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Dna Vaccine ◽  
Protective Immunity ◽  
Acute Toxoplasmosis ◽  
Microneme Protein

Toxoplasma gondii: Protective immunity against experimental toxoplasmosis induced by a DNA vaccine encoding the perforin-like protein 1

2011 ◽  
Vol 128 (1) ◽  
pp. 38-43 ◽  
Author(s):  
Hai-Kuo Yan ◽  
Zi-Guo Yuan ◽  
Eskild Petersen ◽  
Xiu-Xiang Zhang ◽  
Dong-Hui Zhou ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Dna Vaccine ◽  
Protective Immunity

Synergy of mIL-21 and mIL-15 in enhancing DNA vaccine efficacy against acute and chronic Toxoplasma gondii infection in mice

Vaccine ◽  
2014 ◽  
Vol 32 (25) ◽  
pp. 3058-3065 ◽  
Author(s):  
Zhong-Yuan Li ◽  
Jia Chen ◽  
Eskild Petersen ◽  
Dong-Hui Zhou ◽  
Si-Yang Huang ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Dna Vaccine ◽  
Vaccine Efficacy ◽  
Toxoplasma Gondii Infection
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