scholarly journals Raman spectroscopic investigation on the biomedical evolution of spinal cord injury and the therapeutic outcomes of its low-level laser therapy

2022 ◽  
pp. 103337
Author(s):  
Furong Zhang ◽  
Zhuowen Liang ◽  
Dongliang Song ◽  
Zhe Wang ◽  
Kaige Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Spectroscopic Investigation ◽  
Low Level Laser Therapy ◽  
Raman Spectroscopic ◽  
Low Level Laser ◽  
Therapeutic Outcomes ◽  
Level Laser ◽  
Cord Injury

scholarly journals Low-Level Laser Therapy and Spinal Cord Injury: Effects of 3 Different Fluences in the Intermediate Period of Repair in an Experimental Model in Rats

2020 ◽  
Vol 63 ◽  
Author(s):  
Suellen de Oliveira Veronez Silva ◽  
Lívia Assis ◽  
Paula Fernanda Gallani Martin Del Campo ◽  
Katherine Chuere Nunes Duarte ◽  
Flavia de Oliveira ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Experimental Model ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Intermediate Period ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury

scholarly journals Low-level laser therapy for spinal cord injury in rats: effects of polarization

2013 ◽  
Vol 18 (9) ◽  
pp. 098002 ◽  
Author(s):  
Takahiro Ando ◽  
Shunichi Sato ◽  
Hiroaki Kobayashi ◽  
Hiroshi Nawashiro ◽  
Hiroshi Ashida ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury

scholarly journals Label-Free Spectral Imaging Unveils Biochemical Mechanisms of Low-Level Laser Therapy on Spinal Cord Injury

2018 ◽  
Vol 49 (3) ◽  
pp. 1168-1183 ◽  
Author(s):  
Yuze Gong ◽  
Shuang Wang ◽  
Zhuowen Liang ◽  
Zhe Wang ◽  
Xu Zhang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Glial Scar ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury ◽  
Biochemical Mechanisms

Background/Aims: Low-level laser therapy (LLLT) leads to complex photochemical responses during the healing process of spinal cord injury (SCI). Confocal Raman Microspectral Imaging (in combination with multivariate analysis) was adopted to illustrate the underlying biochemical mechanisms of LLLT treatment on a SCI rat model. Methods: Using transversal tissue sections, the Raman spectra can identify areas neighboring the injury site, glial scar, cavity, and unharmed white matter, as well as their correlated cellular alterations, such as demyelination and up-regulation of chondroitin sulfate proteoglycans (CSPGs). Multivariate data analysis methods are used to depict the underlying therapeutic effects by highlighting the detailed content and distribution variations of the biochemical constituents. Results: It is confirmed that photon-tissue interactions might lead to a decay of the inhibitory response to remyelination by suppressing CSPG expression, as also morphologically demonstrated by reduced glial scar and cavity areas. An inter-group comparison semi-quantitatively confirms changes in lipids, phosphatidic acid, CSPGs, and cholesterol during SCI and its LLLT treatment, paving the way for in vitro and in vivo understanding of the biochemical changes accompanying pathobiological SCI events. Conclusion: The achieved results in this work not only have once again proved the well-known cellular mechanisms of SCI, but further illustrate the underlying biochemical variability during LLLT treatment, which provide a sound basis for developing real-time Raman methodologies to monitor the efficacy of the SCI LLLT treatment.

Effects of polarization in low-level laser therapy of spinal cord injury in rats

2012 ◽  
Author(s):  
Takahiro Ando ◽  
Shunichi Sato ◽  
Hiroaki Kobayashi ◽  
Hiroshi Nawashiro ◽  
Hiroshi Ashida ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury

scholarly journals A Review of Low-Level Laser Therapy for Spinal Cord Injury: Challenges And Safety

2020 ◽  
Vol 11 (4) ◽  
pp. 363-368
Author(s):  
Saeed Vafaei-Nezhad ◽  
Mahnaz Pour Hassan ◽  
Mohsen Noroozian ◽  
Abbas Aliaghaei ◽  
Atefeh Shirazi Tehrani ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury

Effects of different fluences of low-level laser therapy in an experimental model of spinal cord injury in rats

2016 ◽  
Vol 32 (2) ◽  
pp. 343-349 ◽  
Author(s):  
Suellen Veronez ◽  
Lívia Assis ◽  
Paula Del Campo ◽  
Flávia de Oliveira ◽  
Gláucia de Castro ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Laser Therapy ◽  
Experimental Model ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Cord Injury

Comparison of the Effects of Electrical Field Stimulation and Low-Level Laser Therapy on Bone Loss in Spinal Cord–Injured Rats

2010 ◽  
Vol 28 (5) ◽  
pp. 669-674 ◽  
Author(s):  
Carla Christina Medalha ◽  
Beatriz Oliveira Amorim ◽  
Jéssica Mayra Ferreira ◽  
Poliane Oliveira ◽  
Rosa Maria Rodrigues Pereira ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Loss ◽  
Laser Therapy ◽  
Electrical Field Stimulation ◽  
Low Level Laser Therapy ◽  
Field Stimulation ◽  
Electrical Field ◽  
Low Level Laser ◽  
Level Laser ◽  
Spinal Cord Injured

Therapeutic Outcomes of Low-Level Laser Therapy for Closed Bone Fracture in the Human Wrist and Hand

2014 ◽  
Vol 32 (4) ◽  
pp. 212-218 ◽  
Author(s):  
Wen-Dien Chang ◽  
Jih-Huah Wu ◽  
Hui-Ju Wang ◽  
Joe-Air Jiang
Keyword(s):  
Laser Therapy ◽  
Bone Fracture ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Therapeutic Outcomes ◽  
Level Laser

Low-Level Laser Therapy Techniques and Equipment for Occupational Disease Prevention in Precision Workers

2021 ◽  
pp. 78-83
Author(s):  
NYu Mal’kova ◽  
MD Petrova
Keyword(s):  
Spinal Cord ◽  
Laser Radiation ◽  
Laser Therapy ◽  
Blood Circulation ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Before And After ◽  
Spinal Cord Disorders

Background: The problem of protecting and maintaining health of workers in the microelectronics industry exposed to adverse occupational factors including tension and overstrain of the muscles of the upper extremities and visual strain, gains special relevance. Objective: Introduction of the developed and patented low-level laser therapy techniques to recover functions of vision and the musculoskeletal system impaired in the course of work. Materials and methods: The study involved 65 chip assemblers aged 26–41 years. Their eyes, the back of the hands, and the collar area were exposed to low-level laser radiation from the red region of the spectrum. All employees were examined by a neurologist and a surgeon and their working conditions were evaluated. The accommodation apparatus was tested using an AKA-01 type accommodation meter. Results: After five 10-minute sessions, we registered an increase in the volume of absolute accommodation during the observation period before and after the work shift by 28 % and 19 %, respectively. On subsequent days of observation, we noted an increase in the accommodation during 10 days, followed by a decrease by the 30th day of observation. Application of preventive techniques helped eliminate spinal cord disorders in all workers. Blood circulation in fingers increased by 66 % compared to the initial condition. Discussion: Low-level laser therapy improves blood supply, intensifies redox processes in the retina of the eye, skin cells, and blood vessels. Conclusions: Low-level laser radiation of the red region of the spectrum relieves the spasm of accommodation and normalizes the efficiency of the accommodation apparatus. Such laser therapy helps eliminate spinal cord disorders and improve blood circulation. Introduction of the developed techniques can prevent occupational diseases and reduce disability in patients.

scholarly journals Raman spectroscopic investigation of spinal cord injury in a rat model

2011 ◽  
Vol 16 (2) ◽  
pp. 027003 ◽  
Author(s):  
Tarun Saxena ◽  
Bin Deng ◽  
Dennis Stelzner ◽  
Julie Hasenwinkel ◽  
Joseph Chaiken
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Rat Model ◽  
Spectroscopic Investigation ◽  
Raman Spectroscopic ◽  
Cord Injury
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