scholarly journals Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge

Virology ◽  
2004 ◽  
Vol 325 (2) ◽  
pp. 192-199 ◽  
Author(s):  
William H Vecino ◽  
Natalie M Quanquin ◽  
Luis Martinez-Sobrido ◽  
Ana Fernandez-Sesma ◽  
Adolfo Garcı́a-Sastre ◽  
...  
Keyword(s):  
Dna Vaccine ◽  
Shigella Flexneri ◽  
Mucosal Immunization ◽  
Influenza Hemagglutinin

scholarly journals Gold-Nanostar-Chitosan-Mediated Delivery of SARS-CoV-2 DNA Vaccine for Respiratory Mucosal Immunization: Development and Proof-of-Principle

ACS Nano ◽  
2021 ◽  
Author(s):  
Uday S. Kumar ◽  
Rayhaneh Afjei ◽  
Katherine Ferrara ◽  
Tarik F. Massoud ◽  
Ramasamy Paulmurugan
Keyword(s):  
Dna Vaccine ◽  
Mucosal Immunization ◽  
Gold Nanostar ◽  
Proof Of Principle

Immunogenicity and protective efficacy of a DNA vaccine encoding a chimeric protein of avian influenza hemagglutinin subtype H5 fused to CD154 (CD40L) in Pekin ducks

Vaccine ◽  
2010 ◽  
Vol 28 (51) ◽  
pp. 8147-8156 ◽  
Author(s):  
Qingxia Yao ◽  
Karl P. Fischer ◽  
Lena Li ◽  
Babita Agrawal ◽  
Yohannes Berhane ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Dna Vaccine ◽  
Protective Efficacy ◽  
Chimeric Protein ◽  
Influenza Hemagglutinin ◽  
Pekin Ducks

scholarly journals Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin

2011 ◽  
Vol 108 (9) ◽  
pp. 3510-3515 ◽  
Author(s):  
Ming-Wei Chen ◽  
Hsin-Yu Liao ◽  
Yaoxing Huang ◽  
Jia-Tsrong Jan ◽  
Chih-Cheng Huang ◽  
...  
Keyword(s):  
Dna Vaccine ◽  
Specific Mutation ◽  
Sugar Binding ◽  
Influenza Hemagglutinin

scholarly journals Oral Administration of Influenza Vaccine in Combination with the Adjuvants LT-K63 and LT-R72 Induces Potent Immune Responses Comparable to or Stronger than Traditional Intramuscular Immunization

2001 ◽  
Vol 8 (3) ◽  
pp. 652-657 ◽  
Author(s):  
John D. Barackman ◽  
Gary Ott ◽  
Samuel Pine ◽  
Derek T. O'Hagan
Keyword(s):  
Immune Responses ◽  
Serum Antibody ◽  
Immunoglobulin A ◽  
Oral Immunization ◽  
Mucosal Immunization ◽  
Influenza Hemagglutinin ◽  
Immunization Strategies ◽  
Specific Immunoglobulin ◽  
Nasal Secretions ◽  
Intragastric Gavage

ABSTRACT Mucosal immunization strategies are actively being pursued in the hopes of improving the efficacy of vaccines against the influenza virus. Our group investigated the oral immunization of mice via intragastric gavage with influenza hemagglutinin (HA) combined with mutant Escherichia coli heat-labile enterotoxins K63 (LT-K63) and R72 (LT-R72). These oral immunizations resulted in potent serum antibody and HA inhibition titers, in some cases stronger than those obtained with traditional intramuscular administration, in addition to HA-specific immunoglobulin A in the saliva and nasal secretions. This study demonstrates that it may be possible to develop effective oral influenza vaccines.

scholarly journals Phase I clinical evaluation of seasonal influenza hemagglutinin (HA) DNA vaccine prime followed by trivalent influenza inactivated vaccine (IIV3) boost

2015 ◽  
Vol 44 ◽  
pp. 112-118 ◽  
Author(s):  
Julie E. Ledgerwood ◽  
Zonghui Hu ◽  
Pamela Costner ◽  
Galina Yamshchikov ◽  
Mary E. Enama ◽  
...  
Keyword(s):  
Phase I ◽  
Dna Vaccine ◽  
Clinical Evaluation ◽  
Seasonal Influenza ◽  
Inactivated Vaccine ◽  
Influenza Hemagglutinin

Mucosal immunization of sheep with a Maedi-Visna virus (MVV) env DNA vaccine protects against early MVV productive infection

Vaccine ◽  
2005 ◽  
Vol 23 (34) ◽  
pp. 4342-4352 ◽  
Author(s):  
Belén González ◽  
Ramsés Reina ◽  
Iker García ◽  
Sara Andrés ◽  
Idoia Glaria ◽  
...  
Keyword(s):  
Dna Vaccine ◽  
Productive Infection ◽  
Mucosal Immunization ◽  
Visna Virus ◽  
Maedi Visna Virus

Mucosal Immunization with a Urease B DNA Vaccine Induces Innate and Cellular Immune Responses Against Helicobacter pylori

Helicobacter ◽  
2006 ◽  
Vol 11 (2) ◽  
pp. 113-122 ◽  
Author(s):  
Caterina Hatzifoti ◽  
Yvonne Roussel ◽  
Andrew G. Harris ◽  
Brendan W. Wren ◽  
John W. Morrow ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Immune Responses ◽  
Dna Vaccine ◽  
Mucosal Immunization ◽  
Cellular Immune Responses ◽  
Cellular Immune

scholarly journals Mucosal immunization with Shigella flexneri outer membrane vesicles induced protection in mice

Vaccine ◽  
2011 ◽  
Vol 29 (46) ◽  
pp. 8222-8229 ◽  
Author(s):  
A.I. Camacho ◽  
J. de Souza ◽  
S. Sánchez-Gómez ◽  
M. Pardo-Ros ◽  
J.M. Irache ◽  
...  
Keyword(s):  
Outer Membrane ◽  
Shigella Flexneri ◽  
Membrane Vesicles ◽  
Outer Membrane Vesicles ◽  
Mucosal Immunization
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