Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes

2012 ◽  
Vol 2012 ◽  
pp. 125-126 ◽  
Author(s):  
R. Ness-Abramof
2013 ◽  
Vol 57 (1) ◽  
pp. 24-25
Author(s):  
Geltrude Mingrone ◽  
Simona Panunzi ◽  
Andrea De Gaetano ◽  
Caterina Guidone ◽  
Amerigo Iaconelli ◽  
...  

2012 ◽  
Vol 366 (17) ◽  
pp. 1577-1585 ◽  
Author(s):  
Geltrude Mingrone ◽  
Simona Panunzi ◽  
Andrea De Gaetano ◽  
Caterina Guidone ◽  
Amerigo Iaconelli ◽  
...  

Author(s):  
Michael Choi ◽  
Miguel Burch

This chapter provides a summary of a landmark study in bariatric surgery. In obese patients with uncontrolled type 2 diabetes, does bariatric surgery plus intensive medical therapy achieve improved glycemic control in significantly more patients than medical therapy alone? Starting with that question, this chapter describes the basics of the study, including funding, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, criticisms, and limitations. The chapter also briefly reviews other relevant studies and information, discusses implications and concludes with a relevant clinical case about bariatric surgery for a morbidly obese female patient with a BMI of 37 and type 2 diabetes.


2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Xiaohu Guo ◽  
Xiaoyan Liu ◽  
Mancai Wang ◽  
Fengxian Wei ◽  
Yawu Zhang ◽  
...  

Objective. To assess the effects of bariatric surgery versus medical therapy for type 2 diabetes mellitus.Methods. The Cochrane library, PubMed, Embase, Chinese biomedical literature database, and Wanfang database up to February 2012 were searched. The literature searches strategies contained terms (“diabetes*”, “surg*”, and “medic*” were used), combined with the medical subject headings. Randomized controlled trails (RCTs) of frequently used bariatric surgery for obese patients with type 2 diabetes were included. Study selection, data extraction, quality assessment, and data analyses were performed according to the Cochrane standards.Results. Three randomized controlled trials (RCTs) involving 170 patients in the bariatric surgery groups and 100 patients in the medical therapy group were selected. Compared with medical therapy, bariatric surgery for type 2 diabetes can significantly decrease the levels of HbA1c, FBG, weight, triglycerides, and the dose of hypoglycemic, antihypertensive, and lipid-lowering medicine, while increasing the rate of diabetes remission (RR = 9.74, 95%CI, (1.36, 69.66)) and the levels of high-density lipoprotein. However, there are no statistical differences in serious adverse events between the surgical and medical groups (RR = 1.23, 95%CI, (0.80, 1.87)).Conclusions. Surgical procedures were more likely to help patients achieve benefits than medical therapy alone. Further intensive RCTs of high-quality, multiple centers and long-term followup should be carried out to provide more reliable evidence.


2018 ◽  
Vol 24 (3) ◽  
pp. 256-264 ◽  
Author(s):  
Megan R. Crawford ◽  
Nathan Pham ◽  
Leila Khan ◽  
James F. Bena ◽  
Philip R. Schauer ◽  
...  

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