Expression of the epidermal growth factor system in endometrioid endometrial cancer

2007 ◽  
Vol 104 (1) ◽  
pp. 158-167 ◽  
Author(s):  
Kirsten Ejskjær ◽  
Boe Sandahl Sørensen ◽  
Steen Seier Poulsen ◽  
Axel Forman ◽  
Ebba Nexø ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Epidermal Growth ◽  
Endometrioid Endometrial Cancer ◽  
Factor System

Expression of the Epidermal Growth Factor System in Eutopic Endometrium from Women with Endometriosis Differs from That in Endometrium from Healthy Women

2009 ◽  
Vol 67 (2) ◽  
pp. 118-126 ◽  
Author(s):  
Kirsten Ejskjær ◽  
Boe Sandahl Sorensen ◽  
Steen Seier Poulsen ◽  
Ole Mogensen ◽  
Axel Forman ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Eutopic Endometrium ◽  
Healthy Women ◽  
Epidermal Growth ◽  
Factor System

Expression of the epidermal growth factor system in human middle ear cholesteatoma

2013 ◽  
Vol 134 (2) ◽  
pp. 124-134 ◽  
Author(s):  
Mette Bendixen Thorup ◽  
Mathias Munk ◽  
Steen Seier Poulsen ◽  
Michael Gaihede ◽  
Ebba Nexo ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Middle Ear ◽  
Middle Ear Cholesteatoma ◽  
Epidermal Growth ◽  
Factor System ◽  
Human Middle Ear

scholarly journals Emerging Therapeutic Biomarkers in Endometrial Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Peixin Dong ◽  
Masanori Kaneuchi ◽  
Yosuke Konno ◽  
Hidemichi Watari ◽  
Satoko Sudo ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Epidermal Growth Factor Receptor ◽  
Endometrial Cancer ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Tumor Cells ◽  
Growth Factor Receptor ◽  
Mesenchymal Transition ◽  
Molecular Therapies ◽  
Epidermal Growth

Although clinical trials of molecular therapies targeting critical biomarkers (mTOR, epidermal growth factor receptor/epidermal growth factor receptor 2, and vascular endothelial growth factor) in endometrial cancer show modest effects, there are still challenges that might remain regarding primary/acquired drug resistance and unexpected side effects on normal tissues. New studies that aim to target both genetic and epigenetic alterations (noncoding microRNA) underlying malignant properties of tumor cells and to specifically attack tumor cells using cell surface markers overexpressed in tumor tissue are emerging. More importantly, strategies that disrupt the cancer stem cell/epithelial-mesenchymal transition-dependent signals and reactivate antitumor immune responses would bring new hope for complete elimination of all cell compartments in endometrial cancer. We briefly review the current status of molecular therapies tested in clinical trials and mainly discuss the potential therapeutic candidates that are possibly used to develop more effective and specific therapies against endometrial cancer progression and metastasis.

Epidermal Growth Factor Receptor Expression and Endometrial Cancer Histotypes

1994 ◽  
Vol 734 (1 The Human End) ◽  
pp. 298-305 ◽  
Author(s):  
VALERIO M. JASONNI ◽  
DONATELLA SANTINI ◽  
ANDREA AMADORI ◽  
CLAUDIO CECCARELLI ◽  
SILVIA NALDI
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Endometrial Cancer ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Growth Factor Receptor ◽  
Receptor Expression ◽  
Epidermal Growth
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