Coordinate expression of cytokeratin 8 and cytokeratin 17 immunohistochemical staining in cervical intraepithelial neoplasia and cervical squamous cell carcinoma: An immunohistochemical analysis and review of the literature

2008 ◽  
Vol 108 (3) ◽  
pp. 598-602 ◽  
Author(s):  
Katsuhide Ikeda ◽  
Genshu Tate ◽  
Takao Suzuki ◽  
Toshiyuki Mitsuya
2009 ◽  
Vol 34 (6) ◽  
pp. 917-925 ◽  
Author(s):  
Mee Lee Looi ◽  
Saiful Anuar Karsani ◽  
Mariati Abdul Rahman ◽  
Ahmad Zailani Hatta Mohd Dali ◽  
Siti Aishah Md Ali ◽  
...  

2021 ◽  
Vol 6 (1) ◽  
pp. 43-47
Author(s):  
Emine Zeynep Tarini ◽  
Hasan İlyas Özardali

Objective. We aimed to demonstrate whether the immunohistochemical expression of C-erb-B2 and progesterone receptors are valuable in the diagnosis of intraepithelial cervical neoplasia and squamous cell carcinoma. Methods and Results. Our retrospective study, a total of 84 cases diagnosed as squamous cell carcinoma and cervical intraepithelial neoplasia during 2005-2009, at the pathology department of Harran University, was investigated and stained with immunohistochemistry. Progesterone receptor was stained positive in 5 of 21 cervical intraepithelial neoplasia I. As a result of the statistical analysis (SPSS statistic 15.0), a significant correlation was found for positive progesterone receptors. No positive staining was seen in any of the cases with CerbB2 (p>0,05). Conclusions. In this study, it was concluded that positive progesterone receptors can be used to distinguish cases of cervical intraepithelial neoplasia I from other dysplasia and carcinoma, while Cerb-B2 has not been shown to be useful in distinguishing between these lesions.


Sign in / Sign up

Export Citation Format

Share Document