Feasibility study and dosimetric evaluation of real time CT-guided intracavitary plus interstitial cervical implantation in an outpatient setting for locally advanced cervical cancer patients

2018 ◽  
Vol 149 ◽  
pp. 161
Author(s):  
J.I. Tang ◽  
V.Y. Koh ◽  
J. Ng ◽  
J. Low
Keyword(s):  
Cervical Cancer ◽  
Real Time ◽  
Cancer Patients ◽  
Feasibility Study ◽  
Locally Advanced ◽  
Outpatient Setting ◽  
Advanced Cervical Cancer ◽  
Ct Guided ◽  
Locally Advanced Cervical Cancer

scholarly journals Oncothermia in HIV-Positive and -Negative Locally Advanced Cervical Cancer Patients in South Africa

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Carrie A. Strauss ◽  
Jeffrey A. Kotzen ◽  
Ans Baeyens ◽  
Irma Maré
Keyword(s):  
South Africa ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Standard Treatment ◽  
Locally Advanced ◽  
External Beam Radiation ◽  
Hiv Positive ◽  
Advanced Cervical Cancer ◽  
Treatment Toxicity ◽  
Locally Advanced Cervical Cancer

Aim. Investigate the clinical, economic, and cellular effects of the addition of oncothermia to standard treatment for HIV-positive and -negative locally advanced cervical cancer patients in public healthcare in South Africa. Objectives. Evaluate the effect that the addition of oncothermia has on local disease control, progression-free survival, overall survival at 2 years, treatment toxicity, quality of life, economic impact, and HIV status of participants. Radiobiology investigations will evaluate thermoradiosensitivity and the molecular markers for thermoradiosensitivity. Methodology. Phase III randomised clinical trial involving 236 HIV-negative and -positive stage IIb-III locally advanced cervical cancer patients. Treatment includes cisplatin, external beam radiation, and brachytherapy. The study group will receive oncothermia treatments. Participants will be monitored for two years after completion of treatment. Hypothesis. The addition of oncothermia to standard treatment protocols will result in improved clinical response without increasing treatment toxicity in HIV-positive patients or raising healthcare costs.

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