scholarly journals Sex-dependent long-term effects of prepubescent stress on the posterior parietal cortex

2021 ◽  
Vol 14 ◽  
pp. 100295
Author(s):  
Mona Fariborzi ◽  
Soo Bin Park ◽  
Ali Ozgur ◽  
Gyorgy Lur
2009 ◽  
Vol 21 (3) ◽  
pp. 581-593 ◽  
Author(s):  
Ilke Öztekin ◽  
Brian McElree ◽  
Bernhard P. Staresina ◽  
Lila Davachi

Functional magnetic resonance imaging was used to identify regions involved in working memory (WM) retrieval. Neural activation was examined in two WM tasks: an item recognition task, which can be mediated by a direct-access retrieval process, and a judgment of recency task that requires a serial search. Dissociations were found in the activation patterns in the hippocampus and in the left inferior frontal gyrus (LIFG) when the probe contained the most recently studied serial position (where a test probe can be matched to the contents of focal attention) compared to when it contained all other positions (where retrieval is required). The data implicate the hippocampus and the LIFG in retrieval from WM, complementing their established role in long-term memory. Results further suggest that the left posterior parietal cortex (LPPC) supports serial retrieval processes that are often required to recover temporal order information. Together, these data suggest that the LPPC, the LIFG, and the hippocampus collectively support WM retrieval. Critically, the reported findings support accounts that posit a distinction between representations maintained in and outside of focal attention, but are at odds with traditional dual-store models that assume distinct mechanisms for short- and long-term memory representations.


2019 ◽  
Author(s):  
V Marija Čolić ◽  
Uroš Konstantinović ◽  
Jovana Bjekić ◽  
R Saša Filipović

AbstractSpatial memory relies on efficient encoding, storage and retrieval of spatial information, which enables us to remember paths or locations of objects in everyday life. Moreover, this type of memory has been shown to decline with age and various neurodegenerative disorders. Parietal cortex has been shown to play an important role in the formation of short-term representations of spatial information. The aim of the current study was to test the possibility of immediate and long-term spatial memory enhancement, by increasing excitability of parietal posterior cortex. We used transcranial direct current stimulation (tDCS) over posterior parietal cortex in a placebo-controlled cross-over study. Participants received anodal (1.5 mA) or sham tDCS stimulation over P4 site (10-20 EEG system) for 20 minutes in two separate sessions. Immediately after stimulation, participants completed a spatial maze task, which consisted of learning block, 2D recall, and 3D recall. Spatial memory performance was tested 24 hours and 7 days after stimulation, to assess potential long-term effects. We found no significant effects of anodal stimulation on spatial memory performance either on immediate or delayed recall. This was the case with both, 2D and 3D spatial memory recall. Our results are in line with some studies that suggest that single brain stimulation sessions do not always produce effects on cognitive functions.


2009 ◽  
Author(s):  
Philip Tseng ◽  
Cassidy Sterling ◽  
Adam Cooper ◽  
Bruce Bridgeman ◽  
Neil G. Muggleton ◽  
...  

2018 ◽  
Author(s):  
Imogen M Kruse

The near-miss effect in gambling behaviour occurs when an outcome which is close to a win outcome invigorates gambling behaviour notwithstanding lack of associated reward. In this paper I postulate that the processing of concepts which are deemed controllable is rooted in neurological machinery located in the posterior parietal cortex specialised for the processing of objects which are immediately actionable or controllable because they are within reach. I theorise that the use of a common machinery facilitates spatial influence on the perception of concepts such that the win outcome which is 'almost complete' is perceived as being 'almost within reach'. The perceived realisability of the win increases subjective reward probability and the associated expected action value which impacts decision-making and behaviour. This novel hypothesis is the first to offer a neurological model which can comprehensively explain many empirical findings associated with the near-miss effect as well as other gambling phenomena such as the ‘illusion of control’. Furthermore, when extended to other compulsive behaviours such as drug addiction, the model can offer an explanation for continued drug-seeking following devaluation and for the increase in cravings in response to perceived opportunity to self-administer, neither of which can be explained by simple reinforcement models alone. This paper therefore provides an innovative and unifying perspective for the study and treatment of behavioural and substance addictions.


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