Acute hemodynamic effects of an alpha- and beta-receptor blocking agent (AH 5158) on the systemic and pulmonary circulation at rest and during exercise in hypertensive patients

1977 ◽  
Vol 93 (5) ◽  
pp. 585-591 ◽  
Author(s):  
Günter Koch
1973 ◽  
Vol 23 ◽  
pp. 35
Author(s):  
Yoichi Maruyama ◽  
Takafumi Ishihara ◽  
Ichiva Hiraki ◽  
Masayoshi Nozaki ◽  
Fumio Takenaka

1988 ◽  
Vol 22 (6) ◽  
pp. 484-485 ◽  
Author(s):  
Gopal Das ◽  
Janine C. Ferris

Beta-receptor blocking agents are commonly used to treat patients with heart disease, and generalized seizures due to therapy with these agents are rare. All reported cases of seizures due to beta blocking agents have occurred only in those subjects who ingested large doses of the drugs. We observed generalized convulsions in a patient who was receiving therapeutic doses of an ultrashort-acting beta-blocking agent (esmolol hydrochloride) intravenously. A literature survey and possible mechanisms by which these agents induce seizures are presented.


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