Utility of positron emission tomography in predicting cardiac events and survival in patients with coronary artery disease and severe left ventricular dysfunction

2001 ◽  
Vol 87 (9) ◽  
pp. 1096-1099 ◽  
Author(s):  
Rajesh Rohatgi ◽  
Shilpi Epstein ◽  
Jaime Henriquez ◽  
Ala’eldin A Ababneh ◽  
Kathleen T Hickey ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Positron Emission Tomography ◽  
Coronary Artery ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Emission Tomography ◽  
Cardiac Events ◽  
Severe Left Ventricular Dysfunction ◽  
Positron Emission ◽  
Artery Disease

scholarly journals Vulnerable plaque imaging using 18F-sodium fluoride positron emission tomography

2020 ◽  
Vol 93 (1113) ◽  
pp. 20190797 ◽  
Author(s):  
Jacek Kwiecinski ◽  
Piotr J Slomka ◽  
Marc R Dweck ◽  
David E Newby ◽  
Daniel S Berman
Keyword(s):  
Coronary Artery Disease ◽  
Positron Emission Tomography ◽  
Coronary Artery ◽  
Sodium Fluoride ◽  
Imaging Modality ◽  
Emission Tomography ◽  
Plaque Morphology ◽  
Non Invasive ◽  
Positron Emission ◽  
Artery Disease

Positron emission tomography (PET) with 18F-sodium fluoride (18F-NaF) has emerged as a promising non-invasive imaging modality to identify high-risk and ruptured atherosclerotic plaques. By visualizing microcalcification, 18F-NaF PET holds clinical promise in refining how we evaluate coronary artery disease, shifting our focus from assessing disease burden to atherosclerosis activity. In this review, we provide an overview of studies that have utilized 18F-NaF PET for imaging atherosclerosis. We discuss the associations between traditional coronary artery disease measures (risk factors) and 18F-NaF plaque activity. We also present the data on the histological validation as well as show how 18F-NaF uptake is associated with plaque morphology on intravascular and CT imaging. Finally, we discuss the technical challenges associated with 18F-NaF coronary PET highlighting recent advances in this area.

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