Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones 1 2 1In accordance with the policy of the University of Colorado Health Sciences Center, D.R., R.H.J.H., and J.B. declare a patent interest in RH1. 2Abbreviations: MMC, mitomycin C; NQO1, NAD(P)H:quinone oxidoreductase 1 or DT-diaphorase; MeDZQ, 2,5-diaziridinyl-3,6-dimethyl-1,4-benzoquinone; DCPIP, 2,6-dichlorophenol-indophenol; MTT, thiazolyl blue; P450R, NADPH:cytochrome P450 reductase; b5R, NADH:cytochrome b5 reductase; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; FBS, fetal bovine serum; and MEM, Eagle’s minimum essential medium.
2001 ◽
Vol 61
(12)
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pp. 1509-1516
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2007 ◽
Vol 2
(5)
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pp. S47
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Keyword(s):
Keyword(s):
DT-diaphorase as a determinant of sensitivity to adriamycin in non-small-cell lung-cancer cell lines
1994 ◽
Vol 59
(2)
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pp. 204-207
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2010 ◽
Vol 5
(5)
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pp. 667-672
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Keyword(s):
2012 ◽
Vol 1
(3)
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pp. 267-272
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Keyword(s):
Keyword(s):