Physiological functions and hormonal regulation of mouse vas deferens protein (AKR1B7) in steroidogenic tissues

2001 ◽  
Vol 130-132 ◽  
pp. 903-917 ◽  
Author(s):  
Antoine Martinez ◽  
Christelle Aigueperse ◽  
Pierre Val ◽  
Marie-Hélène Dussault ◽  
Colette Tournaire ◽  
...  
Keyword(s):  
Hormonal Regulation ◽  
Vas Deferens ◽  
Mouse Vas Deferens ◽  
Physiological Functions

Radioimmunoassay of mouse vas deferens protein: developmental profile and hormonal regulation

1993 ◽  
Vol 138 (1) ◽  
pp. 99-105
Author(s):  
A. Martinez ◽  
M. Berger ◽  
Ch. Jean-Faucher ◽  
G. Veyssière ◽  
Cl. Jean
Keyword(s):  
Hormonal Regulation ◽  
Vas Deferens ◽  
Major Protein ◽  
Adult Males ◽  
Developmental Profile ◽  
Mouse Vas Deferens ◽  
Testosterone Treatment ◽  
Specific Radioimmunoassay ◽  
Testosterone Administration ◽  
Old Mice

ABSTRACT This study investigated the hormonal regulation of the developmental pattern of a major protein of the mouse vas deferens (MVDP) which represents 10% of the vas deferens protein content. Using a specific radioimmunoassay, MVDP was first detected in 10-day-old males and its concentration increased sharply between 10 and 30 days, reaching adult levels at 40 days. In adult males, MVDP disappeared after castration, and testosterone treatment for 15 days was necessary to reverse the effect of castration completely. In 10-day-old mice castrated at birth, MVDP levels were similar to those measured in controls of the same age. Testosterone administration from 1 to 10 days of age did not induce precocious accumulation of MVDP. These results suggested that the neonatal expression of MVDP is independent of androgens. From 10 to 30 days, the increase in MVDP levels was androgen-dependent as shown by the castration and injection experiments. In males castrated at birth, the androgen-induced accumulation of MVDP was greatly reduced in adulthood. This suggested that neonatal androgens are necessary to obtain full expression of the MVDP gene in adults. Journal of Endocrinology (1993) 138, 99–105

scholarly journals EFFECT OF ENKEPHALIN AND SUBSTANCE P ON SYMPATHETIC NERVE TRANSMISSION IN MOUSE VAS DEFERENS

1978 ◽  
Vol 28 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Tomio SEGAWA ◽  
Hiroko MURAKAMI ◽  
Hiroshi OGAWA ◽  
Haruaki YAJIMA
Keyword(s):  
Substance P ◽  
Sympathetic Nerve ◽  
Vas Deferens ◽  
Mouse Vas Deferens

Opioid agonist affinity in the guinea-pig ileum and mouse vas deferens

1990 ◽  
Vol 179 (1-2) ◽  
pp. 129-139 ◽  
Author(s):  
Frank Porreca ◽  
Diane LoPresti ◽  
Susan J. Ward
Keyword(s):  
Guinea Pig ◽  
Vas Deferens ◽  
Guinea Pig Ileum ◽  
Opioid Agonist ◽  
Mouse Vas Deferens ◽  
Agonist Affinity

Varicosity-Schwann Cell Interactions Mediated by ATP in the Mouse Vas Deferens

2005 ◽  
Vol 93 (5) ◽  
pp. 2787-2796 ◽  
Author(s):  
Y. Q. Lin ◽  
M. R. Bennett
Keyword(s):  
Schwann Cell ◽  
Schwann Cells ◽  
Vas Deferens ◽  
P2y Receptors ◽  
Autonomic Nerve ◽  
Nerve Terminals ◽  
Metabotropic Receptors ◽  
Mouse Vas Deferens ◽  
Endogenous Release ◽  
Autonomic Nerve Terminals

Schwann cells, from a variety of sources, are known to possess P2Y purinergic metabotropic receptors. However, it is not known if Schwann cells associated with autonomic nerve terminals possess such receptors and if so whether these receptors are activated by the endogenous release of ATP from the nerve terminals. We show that such Schwann cells in the vas deferens give evoked calcium transients on nerve stimulation. These transients are mediated, at least in part, by the endogenous release of ATP, which acts on Schwann cell P2Y receptors to release calcium from within the cells. This work suggests the possibility that Schwann cells are active participants in the process of junctional transmission in the autonomic nervous system.

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