Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping*

1998 ◽  
Vol 63 (5) ◽  
pp. 540-551 ◽  
Author(s):  
Angela D.M. Kashuba ◽  
Joseph S. Bertino ◽  
Gregory L. Kearns ◽  
J. Steven Leeder ◽  
Alan W. James ◽  
...  
1998 ◽  
Vol 8 (5) ◽  
pp. 403-410 ◽  
Author(s):  
Angela D.M Kashuba ◽  
Anne N. Nafziger ◽  
Gregory L. L. Kearns ◽  
J Steven Leeder ◽  
Carol S. Shirey ◽  
...  

1985 ◽  
Vol 249 (2) ◽  
pp. R186-R191 ◽  
Author(s):  
L. A. Stephenson ◽  
M. A. Kolka

The changes occurring in the esophageal temperature (Tes) thresholds for initiation of heat loss responses as affected by the circadian period and menstrual cycle were studied. Four women exercised at 60% peak Vo2 in 35 degrees C (ambient water vapor pressure 1.73 kPa) for 30 min at 0400 and 1600 during the follicular (F) and luteal (L) phase. Tes, arm sweating rate (msw), and forearm blood flow (FBF) were measured frequently. At rest, Tes averaged 0.3 degrees C higher during L than F at both 0400 and 1600 and approximately 0.4 degrees C higher at 1600 than at 0400 during both phases. During exercise transients, the slopes of the FBF:Tes and the msw:Tes relationships were not different among treatments. The thresholds for initiation of sweating and cutaneous vasodilation were higher at 1600 than 0400 during both phases. Thresholds during F at 0400 averaged 36.44 degrees C for msw and 36.80 degrees C for vasodilation. The thresholds during L at 1600 averaged 37.46 and 37.53 degrees C for sweating and vasodilation, respectively. Our data indicate that the thermoregulatory effector activity during exercise is a function of numerous inputs, and one of these may be hormonal or hormonal-like in action. Controlling time of day and menstrual cycle phase are as important as controlling for aerobic power, age, and fitness in studying female thermoregulatory responses during exercise.


2009 ◽  
Vol 106 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Marie K. Hoeger Bement ◽  
Rebecca L. Rasiarmos ◽  
John M. DiCapo ◽  
Audrey Lewis ◽  
Manda L. Keller ◽  
...  

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