Lack of effect of LY314582 (a group 2 metabotropic glutamate receptor agonist) on phencyclidine-induced locomotor activity in metabotropic glutamate receptor 2 knockout mice

Metabotropic Glutamate ◽

Group 2 ◽

The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice

European Journal of Neuroscience ◽

10.1111/ejn.13539 ◽

2017 ◽

Vol 45 (7) ◽

pp. 912-921 ◽

Cited By ~ 5

Author(s):

Thomas Boerner ◽

Alexei M. Bygrave ◽

Jingkai Chen ◽

Anushka Fernando ◽

Stephanie Jackson ◽

...

Keyword(s):

Working Memory ◽

Receptor Antagonist ◽

Glutamate Receptor ◽

Knockout Mice ◽

Receptor Agonist ◽

Spatial Working Memory ◽

D2 Receptor ◽

Metabotropic Glutamate ◽

ChemInform Abstract: Design, Synthesis, and Pharmacological Characterization of (+)-2- Aminobicyclo(3.1.0)hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvul

ChemInform ◽

10.1002/chin.199722076 ◽

2010 ◽

Vol 28 (22) ◽

pp. no-no

Author(s):

J. A. MONN ◽

M. J. VALLI ◽

S. M. MASSEY ◽

R. A. WRIGHT ◽

C. R. SALHOFF ◽

...

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Pharmacological Characterization ◽

Design Synthesis ◽

Metabotropic Glutamate ◽

Group 2 ◽

Orally Active

Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

Journal of Medicinal Chemistry ◽

10.1021/jm9606756 ◽

1997 ◽

Vol 40 (4) ◽

pp. 528-537 ◽

Cited By ~ 299

Author(s):

James A. Monn ◽

Matthew J. Valli ◽

Steven M. Massey ◽

Rebecca A. Wright ◽

Craig R. Salhoff ◽

...

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Pharmacological Characterization ◽

Design Synthesis ◽

Metabotropic Glutamate ◽

Group 2 ◽

Orally Active

The Novel Metabotropic Glutamate Receptor Agonist 2 R ,4 R -APDC Potentiates Stimulation of Phosphoinositide Hydrolysis in the Rat Hippocampus by 3,5-dihydroxyphenylglycine: Evidence for a Synergistic Interaction Between Group 1 and Group 2 Receptors

Neuropharmacology ◽

10.1016/s0028-3908(96)00121-9 ◽

1996 ◽

Vol 35 (12) ◽

pp. 1661-1672 ◽

Cited By ~ 74

Author(s):

D.D SCHOEPP ◽

C.R SALHOFF ◽

R.A WRIGHT ◽

B.G JOHNSON ◽

J.P BURNETT ◽

...

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Rat Hippocampus ◽

The Novel ◽

Metabotropic Glutamate ◽

Group 2 ◽

Stimulation Of ◽

Group 1

A novel orally active Group 2 metabotropic glutamate receptor agonist

Neuroreport ◽

10.1097/00001756-199704140-00027 ◽

1997 ◽

Vol 8 (6) ◽

pp. 1463-1465 ◽

Cited By ~ 20

Author(s):

Ann Bond ◽

James A. Monn ◽

David Lodge

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Active Group ◽

Metabotropic Glutamate ◽

Group 2 ◽

Orally Active

The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease mice

Neurobiology of Disease ◽

10.1016/j.nbd.2012.03.025 ◽

2012 ◽

Vol 47 (1) ◽

pp. 75-91 ◽

Cited By ~ 25

Author(s):

A. Reiner ◽

D.C. Lafferty ◽

H.B. Wang ◽

N. Del Mar ◽

Y.P. Deng

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate ◽

Group 2 ◽

Motor Abnormalities ◽

(2S,1‘S,2‘R,3‘R)-2-(2‘-Carboxy-3‘-hydroxymethylcyclopropyl) Glycine Is a Highly Potent Group 2 and 3 Metabotropic Glutamate Receptor Agonist with Oral Activity

Journal of Medicinal Chemistry ◽

10.1021/jm030967o ◽

2004 ◽

Vol 47 (2) ◽

pp. 456-466 ◽

Cited By ~ 29

Author(s):

Iván Collado ◽

Concepción Pedregal ◽

Ana Belén Bueno ◽

Alicia Marcos ◽

Rosario González ◽

...

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Metabotropic Glutamate ◽

Oral Activity ◽

Group 2 ◽

EFFECTS OF GROUP III METABOTROPIC GLUTAMATE RECEPTOR AGONIST ON THE MICTURITION REFLEX IN URETHANE-ANESTHETIZED RATS

10.26226/morressier.59b63e3fd462b8029238916e ◽

2017 ◽

Author(s):

Masashi Honda

Keyword(s):

Glutamate Receptor ◽

Receptor Agonist ◽

Group Iii ◽

Micturition Reflex ◽

Metabotropic Glutamate ◽

Anesthetized Rats ◽

Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/0960-894x(95)00013-j ◽

1995 ◽

Vol 5 (3) ◽

pp. 223-228 ◽

Cited By ~ 30

Author(s):

S. Richard Baker ◽

John Goldsworthy ◽

Raymond C. Harden ◽

Craig R. Salhoff ◽

Darryle D. Schoepp

Keyword(s):

Glutamate Receptor ◽

Pharmacological Activity ◽

Receptor Agonist ◽

Enzymatic Resolution ◽

Metabotropic Glutamate ◽

Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

European Journal of Pharmacology ◽

10.1016/0014-2999(94)90624-6 ◽

1994 ◽

Vol 256 (1) ◽

pp. 109-112 ◽

Cited By ~ 90

Author(s):

Valeria Bruno ◽

Agata Copani ◽

Giuseppe Battaglia ◽

Rocco Raffaele ◽

Huruiko Shinozaki ◽

...

Keyword(s):

Protective Effect ◽

Glutamate Receptor ◽

Neuronal Death ◽

Receptor Agonist ◽

Metabotropic Glutamate ◽

Excitotoxic Neuronal Death ◽