Intracellular calcium measurements in individual human sperm demonstrate that the majority can respond to progesterone**Supported by a Vacation Scholarship Award from the Wellcome Trust.

1995 ◽  
Vol 64 (6) ◽  
pp. 1213-1215 ◽  
Author(s):  
Andrea Plant ◽  
Eileen A. McLaughlin ◽  
W. Christopher L. Ford
Keyword(s):  
Intracellular Calcium ◽  
Human Sperm ◽  
Individual Human

Luteinizing hormone modulates intracellular calcium, protein tyrosine phosphorylation and motility during human sperm capacitation

2017 ◽  
Vol 483 (2) ◽  
pp. 834-839 ◽  
Author(s):  
Aideé S. López-Torres ◽  
María E. González-González ◽  
Esperanza Mata-Martínez ◽  
Fernando Larrea ◽  
Claudia L. Treviño ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Intracellular Calcium ◽  
Tyrosine Phosphorylation ◽  
Human Sperm ◽  
Protein Tyrosine Phosphorylation ◽  
Sperm Capacitation ◽  
Protein Tyrosine

scholarly journals Acetylcholine causes an increase of intracellular calcium in human sperm

2005 ◽  
Vol 11 (12) ◽  
pp. 881-889 ◽  
Author(s):  
C. Bray ◽  
J.-H. Son ◽  
S. Meizel
Keyword(s):  
Intracellular Calcium ◽  
Human Sperm

TRPV4 is endogenously expressed in vertebrate spermatozoa and regulates intracellular calcium in human sperm

2016 ◽  
Vol 473 (4) ◽  
pp. 781-788 ◽  
Author(s):  
Ashutosh Kumar ◽  
Rakesh Kumar Majhi ◽  
Nirlipta Swain ◽  
S.C. Giri ◽  
Sujata Kar ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Human Sperm

Relationship between hyperactivation and intracellular calcium of human sperm.

2001 ◽  
Vol 76 (3) ◽  
pp. S194
Author(s):  
M Munire ◽  
Y Shimizu ◽  
Y Sakata ◽  
R Minaguchi ◽  
T Aso ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Human Sperm

Low physiological levels of prostaglandins E2 and F2α improve human sperm functions

2016 ◽  
Vol 28 (4) ◽  
pp. 434 ◽  
Author(s):  
Mariana Rios ◽  
Daniela V. Carreño ◽  
Carolina Oses ◽  
Nelson Barrera ◽  
Bredford Kerr ◽  
...  
Keyword(s):  
Intracellular Calcium ◽  
Sperm Motility ◽  
Acrosome Reaction ◽  
Seminal Fluid ◽  
Human Sperm ◽  
Human Spermatozoa ◽  
Control Solution ◽  
Prostaglandins E2 And F2α ◽  
Motility Parameters ◽  
Sperm Functions

Prostaglandins (PGs) have been reported to be present in the seminal fluid and cervical mucus, affecting different stages of sperm maturation from spermatogenesis to the acrosome reaction. This study assessed the effects of low physiological PGE2 and PGF2α concentrations on human sperm motility and on the ability of the spermatozoa to bind to the zona pellucida (ZP). Human spermatozoa were isolated from seminal samples with normal concentration and motility parameters and incubated with 1 μM PGE2, 1 μM PGF2α or control solution to determine sperm motility and the ability to bind to human ZP. The effects of both PGs on intracellular calcium levels were determined. Incubation for 2 or 18 h with PGE2 or PGF2α resulted in a significant (P < 0.05) increase in the percentage of spermatozoa with progressive motility. In contrast with PGF2α, PGE2 alone induced an increase in sperm intracellular calcium levels; however, the percentage of sperm bound to the human ZP was doubled for both PGs. These results indicate that incubation of human spermatozoa with low physiological levels of PGE2 or PGF2α increases sperm functions and could improve conditions for assisted reproduction protocols.

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