Genetic predictors of spontaneous viral elimination or chronic liver disease in hepatitis C infection

2001 ◽  
Vol 120 (5) ◽  
pp. A7-A7
Author(s):  
S ROSS ◽  
S MASCHERETTI ◽  
H HINRICHSEN ◽  
P BUGGISCH ◽  
U FOELSCH ◽  
...  
2001 ◽  
Vol 120 (5) ◽  
pp. A7 ◽  
Author(s):  
Susanne Ross ◽  
Silvia M. Mascheretti ◽  
Holger M. Hinrichsen ◽  
Peter Buggisch ◽  
Ulrich R. Foelsch ◽  
...  

2018 ◽  
Vol 10 (2) ◽  
pp. 37-41
Author(s):  
Farrokh Rad ◽  
Ebrahim Ghaderi ◽  
Bahram Nikkhoo ◽  
Mohammad Aziz Rasouli

Abstract Introduction. Hepatitis C virus (HCV) infection is one of the factors which can lead to a chronic liver disease and hepatocellular carcinoma. There have been several reports on the association of oral lichen planus with hepatic disorders, i.e. hepatitis C infection in particular. Considering the controversies about the association of lichen planus with HCV infection on one hand and considerable impact of hepatitis C on the occurrence of chronic liver disease on the other hand, we investigated the association between lichen planus and HCV infection in Sanandaj City. Methods. This cross sectional study included 168 patients with lichen planus, who were referred to the Dermatology Clinic of Besat Hospital between 2014 and 2016. The diagnosis of lichen planus was made by our dermatologist and HCV antibody titer was determined for every patient. Results. Mean age of the patients was 39.7±13.3 years and mean duration of the disease was 14.8 months. 107 (63.7%) patients were men. The highest frequency of lichen planus was recorded in the housewives (30.4%). In 52 (31%) patients the genital area was involved and it was the most common site. In 6 (3.6%) patients the oral mucosa was involved and it was the least common site in our study. Only 4 (2.7%) patients had family history of lichen planus. None of 168 patients included in this study was found to have HCV infection. Conclusion. In this study, we found no relationship between lichen planus and HCV infection. Yet, the exact mechanism underlying the occurrence of lichen planus in the patients with HCV infection has not been determined. Therefore more studies on this subject are recommended.


2002 ◽  
Vol 67 (4) ◽  
pp. 436-442 ◽  
Author(s):  
G Thomas Strickland ◽  
Alan Fix ◽  
Mohamed Abdel-Hamid ◽  
Nabiel Nh Mikhail ◽  
Imam Waked ◽  
...  

2001 ◽  
Vol 34 ◽  
pp. 114
Author(s):  
H.M. Hinrichsen ◽  
S. Ross ◽  
S. Mascheretti ◽  
P. Buggisch ◽  
U.R. Foelsch ◽  
...  

2018 ◽  
Vol 25 (11) ◽  
pp. 1701-1706
Author(s):  
Muhammad Luqman Farrukh Nagi ◽  
Shafia Manan ◽  
Arjumand Shaheen ◽  
Maheer Amjad ◽  
Maryam Farooq ◽  
...  

Background: Chronic Liver Disease is frequently related with psychiatricco morbidity disorders like depression and anxiety. Psychological disorders are a directmanifestation of Hepatitis C infection. Objectives: The objective was to assess the frequency ofdepression among patients of CLD presenting to the Shalamar Hospital, Lahore a tertiary careprivate institution. Study Design: Cross-sectional study. Setting: Shalamar Hospital Lahore,Pakistan a tertiary care private institution. Period: Four months period (June till September2015). Methods: It was carried out on a convenience sample of 200 patients admitted inShalamar Hospital, Lahore. The HADS questionnaire was used to assess the frequency ofdepression among the patients suffering from chronic Liver Diseases. The selected participantswere meticulously briefed and signed informed consent was acquired. Selected patients werefurther comprehensively briefed about the study and confidentiality, anonymity and privacy ofthe participants was preserved. Ethical approval was sought from Institutional Ethical ReviewBoard of Shalamar Institute of Health Sciences. The data entry and statistical analyses weredone using SPSS version 20. Results: The response rate was 97%. Amongst all, 53% (n =102) were males and 47% (n = 91) were females. About 80% (n = 155) were married whereas 20% (n = 38) were unmarried. Among all patients of chronic liver disease 65% (n = 124)were positive for Hepatitis C Virus Antibody, while 25% (n = 49) were positive for Hepatitis BS Antigen. Of all the participants 32% (n = 61) received blood transfusions and almost 58% (n= 111) had a close family member who suffered from Hepatitis C. About 53% (n = 102) of thepatients were suffering from borderline or clinical depression (p < .000), whereas 56% (n = 108)of the participants suffered from borderline or clinical anxiety (p < .000). Conclusion: Patientssuffering chronically with Hepatitis C have higher than normal occurrence of depression andanxiety symptoms.


1991 ◽  
Vol 13 ◽  
pp. S40-S41
Author(s):  
S. Magrin ◽  
A. Craxì ◽  
C. Fabiano ◽  
G. Fiorentino ◽  
P. Almasio ◽  
...  

2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Dr. Moni Chaudhary

Hepatitis C virus (HCV) infection is the leading cause of chronic liver disease which affects over 150 million individuals worldwide. Without treatment, one third of patients will develop cirrhosis and complications of end-stage liver disease. In India, the majority of chronic liver disease and related deaths are attributable to hepatitis C. People with HCV infection are likely to have poorer health related quality of life, physical, mental, psychosocial and neuropsychiatric problems. These problems are challenges for management of HCV infection. Mental health treatment is considered crucial in the overall management of HCV infection. A supportive environment and a nonjudgmental healthcare team are required for optimal medical and psychological management of patients with HCV. We present a comparison between mental health of patients with HCV infection in India and globally.


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