Peptic ulcer disease in Finland-incidence of surgery, mortality and hospital admissions for the disease during the past 25 years

AbstractPeptic ulcer disease has been a major problem in the Royal Navy for more than 50 years. During the past decade specialist gastroenterology services have been established in an attempt to conserve and retain manpower skills. Fibreoptic endoscopy now provides rapid and accurate diagnosis while treatment with the new H2 receptor antagonists permits safe and effective therapy for the sailor both outside hospital and often now while still at sea. Changes in surgical techniques and a combined medical/surgical policy towards the peptic ulcer patient have also contributed to a coordinated programme.The result of these changes has been a reduction in hospital admissions for duodenal ulcer, in the number of days of work lost from peptic ulcer disease, and a decline in the number of surgical operations for peptic ulcer at RNH Haslar. Invaliding of patients from the Royal Navy and Royal Marines for peptic ulcer disease has been almost abolished, emphasising the success of our policy of manpower conservation. Further work is required, however, to maintain patients in remission from their ulcer for longer periods and to identify better and earlier those patients who will ultimately require surgery.

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Has Peptic Ulcer Disease Changed During the Past Ten Years in Korea? A Prospective Multi-center Study

Digestive Diseases and Sciences ◽

10.1007/s10620-007-0028-6 ◽

2007 ◽

Vol 53 (6) ◽

pp. 1527-1531 ◽

Cited By ~ 53

Author(s):

Hyun Joo Jang ◽

Min Ho Choi ◽

Woon Geon Shin ◽

Kyung Ho Kim ◽

Yong Woo Chung ◽

...

Keyword(s):

Peptic Ulcer ◽

Peptic Ulcer Disease ◽

Ulcer Disease ◽

The Past ◽

Multi Center Study ◽

Center Study

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Decreasing prevalence combined with increasing eradication of Helicobacter pylori infection in the United States has not resulted in fewer hospital admissions for peptic ulcer disease-related complications

Alimentary Pharmacology & Therapeutics ◽

10.1111/j.1365-2036.2007.03340.x ◽

2007 ◽

Vol 25 (12) ◽

pp. 1423-1427 ◽

Cited By ~ 44

Author(s):

D. MANUEL ◽

A. CUTLER ◽

J. GOLDSTEIN ◽

M. B. FENNERTY ◽

K. BROWN

Keyword(s):

United States ◽

Helicobacter Pylori ◽

Peptic Ulcer ◽

Peptic Ulcer Disease ◽

Hospital Admissions ◽

The United States ◽

Helicobacter Pylori Infection ◽

Ulcer Disease

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Medical Tretment of Peptic Ulcer Disease: Should the Emphasis Be Altered in View of Laparoscopic Surgery

Canadian Journal of Gastroenterology ◽

10.1155/1994/392061 ◽

1994 ◽

Vol 8 (3) ◽

pp. 199-204

Author(s):

ABR Thomson

Keyword(s):

Helicobacter Pylori ◽

Peptic Ulcer ◽

Laparoscopic Surgery ◽

Peptic Ulcer Disease ◽

Receptor Antagonist ◽

Proton Pump ◽

Ulcer Disease ◽

The Past ◽

Pros And Cons ◽

Surgical Option

In the past H2-receptor antagonist era, there was initially a lull as more and more ‘me-too’ drugs were developed. Then came the excitement of the proton pump inhibitors and the controversy of the pros and cons of moderate versus potent acid inhibition. The most recent explosion of knowledge has been in the discussion of pH versusHelicobacter pylori, but on the horizon is lurking the promise of the resurgence of the surgical option.

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Peptic ulcer disease: changes it has undergone over the past 50 years

Clinical Medicine (Russian Journal) ◽

10.30629/0023-2149-2020-98-8-583-587 ◽

2021 ◽

Vol 98 (8) ◽

pp. 583-587

Author(s):

A. A. Sheptulin ◽

S. S. Kardasheva ◽

A. A. Kurbatova

Keyword(s):

Peptic Ulcer ◽

Peptic Ulcer Disease ◽

Eradication Therapy ◽

Ulcer Disease ◽

Gastroduodenal Ulcers ◽

The Past ◽

Anti Inflammatory ◽

Ulcerative Lesions ◽

H Pylori

This review considers the main changes in our understanding of the etiology of peptic ulcer disease (PUD), its treatment and prevention. It is emphasized that the discovery of H. pylori infection and the implementation of eradication therapy did not solve all the issues related to PUD. Further investigation is needed to study the pathogenesis of idiopathic gastroduodenal ulcers, as well as ulcerative lesions of the stomach and duodenum, caused by various medications (non-steroidal anti-inflammatory drugs in particular).

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Current status of peptic ulcer disease in Port Harcourt metropolis, Nigeria

African Health Sciences ◽

10.4314/ahs.v20i3.50 ◽

2020 ◽

Vol 20 (3) ◽

pp. 1446-1451

Author(s):

Emeka Ray-Offor ◽

Kalanne Ada Opusunju

Keyword(s):

Duodenal Ulcer ◽

Peptic Ulcer ◽

Gastric Ulcer ◽

Peptic Ulcer Disease ◽

Blood Group ◽

Hospital Admissions ◽

Current Status ◽

Gastric Ulcers ◽

Ulcer Disease ◽

Port Harcourt

Background: Epidemiological studies on peptic ulcer disease (PUD) have shown a recent decrease in hospital admissions in Western countries. Objective: This paper aimed to study the current status and risk factors of PUD in a Nigerian metropolis. Methods: A cross-sectional study of symptomatic patients at upper gastrointestinal (GI) endoscopy diagnosed with PUD from February 2014 to September 2019 at a referral endoscopy facility in Port Harcourt, Niger delta region of Nigeria. The variables studied included demographics, symptoms and duration, blood group, chronic non-steroidal anti-inflammatory (NSAID) use, smoking, endoscopic and histology findings. Statistical analysis was performed using SPSS version 20. Results: A total of 434 upper GI endoscopies were performed during the study period with thirty-one diagnosis of PUD made. The mean age of gastric ulcer (GU) and duodenal ulcer (DU) cases were 54.4 ± 20.2yrs and 48.1 ± 14.5yrs respectively (p = 0.367). GU to DU ratio was 1.4:1. H. pylori infection, chronic NSAID use and blood group O were seen in 7(22.5%), 8(25.8%) and 18(72.0%) respectively. Major indication in 21(67.7%) cases was gastrointestinal bleeding. Conclusion: There is a low diagnostic rate of PUD (6.7%) with pre-pyloric antral gastric ulcers as most common type and multifactorial aetiology. Keywords: Gastric ulcer; duodenal ulcer; endoscopy.

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