Genetic testing for high-risk colon cancer patients1 1Abbreviations used in this paper: FAP, familial adenomatous polyposis; HMPS, hereditary mixed polyposis syndrome; HNPCC, hereditary nonpolyposis colon cancer; JPS, juvenile polyposis; MMR, mutation mismatch repair; MSI, microsatellite instability; PJS, Peutz-Jeghers syndrome; TGF, transforming growth factor.

2003 ◽  
Vol 124 (6) ◽  
pp. 1574-1594 ◽  
Author(s):  
William M. Grady
Keyword(s):  
Colon Cancer ◽  
Genetic Testing ◽  
Growth Factor ◽  
High Risk ◽  
Transforming Growth Factor ◽  
Adenomatous Polyposis ◽  
Polyposis Syndrome ◽  
Hereditary Nonpolyposis Colon Cancer ◽  
Hereditary Nonpolyposis ◽  
Peutz Jeghers Syndrome

Genetic Testing Redefines Hereditary Nonpolyposis Colon Cancer

2015 ◽  
pp. 74-83
Author(s):  
Jean-Marie Buerstedde ◽  
Yuri K. Maliaka ◽  
Nikolay P. Bochkov ◽  
Rodney J. Scott ◽  
Hansjakob M�ller
Keyword(s):  
Colon Cancer ◽  
Genetic Testing ◽  
Hereditary Nonpolyposis Colon Cancer ◽  
Hereditary Nonpolyposis

scholarly journals Hereditary Colon Cancer

1997 ◽  
Vol 11 (5) ◽  
pp. 421-423 ◽  
Author(s):  
Dawna M Gilchrist
Keyword(s):  
Colon Cancer ◽  
Familial Adenomatous Polyposis ◽  
North American Population ◽  
Adenomatous Polyposis ◽  
American Population ◽  
Hereditary Nonpolyposis Colon Cancer ◽  
Hereditary Colon Cancer ◽  
The North ◽  
Hereditary Nonpolyposis ◽  
Tumour Initiation

Hereditary colon cancer comprises approximately 10% of total colon cancer, a disease that affects 6% of the North American population. Knowledge of molecular genetics of familial adenomatous polyposis and hereditary nonpolyposis colon cancer has improved our diagnostic abilities and management, as well as furthered our understanding of the mechanisms of tumour initiation and progression.

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