Commentary on ‘familial Adenomatous Polyposis, Hereditary Nonpolyposis Colon Cancer, and Familial Risk’ by Thorson and Faria

2000 ◽  
Vol 9 (4) ◽  
pp. 699-701
Author(s):  
Ann Lowry
Keyword(s):  
Colon Cancer ◽  
Familial Adenomatous Polyposis ◽  
Familial Risk ◽  
Adenomatous Polyposis ◽  
Hereditary Nonpolyposis Colon Cancer ◽  
Hereditary Nonpolyposis

scholarly journals Hereditary Colon Cancer

1997 ◽  
Vol 11 (5) ◽  
pp. 421-423 ◽  
Author(s):  
Dawna M Gilchrist
Keyword(s):  
Colon Cancer ◽  
Familial Adenomatous Polyposis ◽  
North American Population ◽  
Adenomatous Polyposis ◽  
American Population ◽  
Hereditary Nonpolyposis Colon Cancer ◽  
Hereditary Colon Cancer ◽  
The North ◽  
Hereditary Nonpolyposis ◽  
Tumour Initiation

Hereditary colon cancer comprises approximately 10% of total colon cancer, a disease that affects 6% of the North American population. Knowledge of molecular genetics of familial adenomatous polyposis and hereditary nonpolyposis colon cancer has improved our diagnostic abilities and management, as well as furthered our understanding of the mechanisms of tumour initiation and progression.

What's New in Hereditary Colorectal Cancer?

2005 ◽  
Vol 129 (11) ◽  
pp. 1380-1384 ◽  
Author(s):  
Jeremy R. Jass
Keyword(s):  
Colorectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Hereditary Nonpolyposis Colorectal Cancer ◽  
Practical Significance ◽  
Adenomatous Polyposis ◽  
Repair Gene ◽  
Attenuated Familial Adenomatous Polyposis ◽  
Dna Repair Gene ◽  
Hereditary Nonpolyposis ◽  
Revised Bethesda Guidelines

Abstract Precancerous polyposes other than classic familial adenomatous polyposis and the condition hereditary nonpolyposis colorectal cancer, or Lynch syndrome, continue to present major diagnostic challenges for the anatomic pathologist. This editorial highlights the practical significance of novel insights and clinical guidelines in the recent literature, as well as in 4 contributions to this edition of the Archives of Pathology & Laboratory Medicine. The first section will address attenuated familial adenomatous polyposis and a newly recognized type of autosomal-recessive adenomatous polyposis associated with the DNA repair gene MYH. The remainder of the editorial discusses the role of the revised Bethesda guidelines in the diagnosis of hereditary nonpolyposis colorectal cancer and concludes with the recently identified serrated pathway syndrome.

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