Introduction: We aimed to provide a practical and evidence-based guide on the indications, performance
and reporting of high-resolution oesophageal manometry (HRM) and ambulatory pH monitoring
(PHM) in adult patients in Singapore.
Methods: The guideline committee comprised local gastroenterologists from public and private sectors
with particular expertise in aspects of HRM and PHM, and it was tasked to produce evidence-based
statements on the indications, performance and reporting of these tests. Each committee member
performed literature searches to retrieve relevant articles within the context of domains to which they
were assigned.
Results: Twelve recommendation statements were created and summarised.
Conclusion: Standardising key aspects of HRM and PHM is imperative to ensure the delivery of
high-quality care. We reported the development of recommendations for the performance and
interpretation of HRM and ambulatory reflux monitoring in Singapore.
Keywords: Gastro-oesophageal reflux disease, GERD, high-resolution oesophageal manometry,
oesophagus, pH testing