scholarly journals Tu1647 - The Role of Dectin-1 and Mast Cells in Visceral Hypersensitivity in Patients with Diarrhea-Predominant Irritable Bowel Syndrome

2018 ◽  
Vol 154 (6) ◽  
pp. S-980-S-981
Author(s):  
Chao Li ◽  
Yan Chi
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

scholarly journals Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome

2004 ◽  
Vol 5 (4) ◽  
pp. 319 ◽  
Author(s):  
Jun Ho La ◽  
Tae Wan Kim ◽  
Tae Sik Sung ◽  
Hyun Ju Kim ◽  
Jeom Yong Kim ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Rat Model ◽  
Visceral Hypersensitivity ◽  
Mucosal Mast Cells ◽  
Irritable Bowel

scholarly journals Prostaglandin E2, Produced by Mast Cells in Colon Tissues From Patients With Irritable Bowel Syndrome, Contributes to Visceral Hypersensitivity in Mice

2020 ◽  
Vol 158 (8) ◽  
pp. 2195-2207.e6 ◽  
Author(s):  
Gintautas Grabauskas ◽  
Xiaoyin Wu ◽  
Jun Gao ◽  
Ji-Yao Li ◽  
Danielle Kim Turgeon ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Prostaglandin E2 ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

Sensitivity Testing in Irritable Bowel Syndrome With Rectal Capsaicin Stimulations: Role of TRPV1 Upregulation and Sensitization in Visceral Hypersensitivity?

2014 ◽  
Vol 109 (1) ◽  
pp. 99-109 ◽  
Author(s):  
Sander J M van Wanrooij ◽  
Mira M Wouters ◽  
Lukas Van Oudenhove ◽  
Winde Vanbrabant ◽  
Stéphanie Mondelaers ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Visceral Hypersensitivity ◽  
Sensitivity Testing ◽  
Irritable Bowel

Possible role of nitric oxide in visceral hypersensitivity in patients with irritable bowel syndrome

2006 ◽  
Vol 18 (2) ◽  
pp. 115-122 ◽  
Author(s):  
s. d. kuiken ◽  
t. k. klooker ◽  
g. n. tytgat ◽  
a. lei ◽  
g. e. boeckxstaens
Keyword(s):  
Nitric Oxide ◽  
Irritable Bowel Syndrome ◽  
Visceral Hypersensitivity ◽  
Irritable Bowel

scholarly journals Morphological manifestations of irritable bowel syndrome

2021 ◽  
Vol 55 (2) ◽  
pp. 108-114
Author(s):  
Yu.M. Stepanov ◽  
I.Ya. Budzak ◽  
Yu.A. Gaidar
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Tight Junctions ◽  
Intestinal Mucosa ◽  
Morphological Changes ◽  
Low Grade ◽  
Intercellular Contacts ◽  
Irritable Bowel ◽  
Low Grade Inflammation

The article presents modern data on morphological changes in the intestinal mucosa in patients with irritable bowel syndrome. There were analyzed the studies of different years on the morphological manifestations of irritable bowel syndrome. It has been shown that this pathology has an unusual low-grade inflammation. Mast cells play an important role in these inflammatory disorders, they have an effect on motility disorders, visceral hypersensitivity and other pathogenetic factors of irritable bowel syndrome. Disorders of intercellular tight junctions in this category of patients were also analyzed. The role of proteins involved in intercellular contacts (occludin, claudin, ZO) has been characterized. An analysis of the studies investigating these disorders has been carried out. The article provides examples of the analysis of biopsies in patients with irritable bowel syndrome using various methods of their assessment.

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