Mo1202 LONG-TERM TREATMENT WITH PROTON PUMP INHIBITORS AND TOPICAL STEROIDS IN EOSINOPHILIC ESOPHAGITIS: EFFICACY AND FACTORS INFLUENCING RESPONSE

2020 ◽  
Vol 158 (6) ◽  
pp. S-825
Author(s):  
Matteo Ghisa ◽  
Giorgio Laserra ◽  
Brigida Barberio ◽  
Salvatore Tolone ◽  
Nicola de Bortoli ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Eosinophilic Esophagitis ◽  
Term Treatment ◽  
Topical Steroids ◽  
Factors Influencing ◽  
Long Term Treatment

scholarly journals Long-term Treatment With Proton Pump Inhibitors Is Effective in Children With Eosinophilic Esophagitis

2018 ◽  
Vol 67 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Carolina Gutiérrez-Junquera ◽  
Sonia Fernández-Fernández ◽  
M. Luz Cilleruelo ◽  
Ana Rayo ◽  
Luis Echeverría ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Eosinophilic Esophagitis ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Simone Janett ◽  
Pietro Camozzi ◽  
Gabriëlla G. A. M. Peeters ◽  
Sebastiano A. G. Lava ◽  
Giacomo D. Simonetti ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Term Treatment ◽  
Cross Sectional ◽  
Magnesium Metabolism ◽  
Poor Renal Function ◽  
Long Term Treatment

In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature. Hypomagnesemia, mostly associated with hypocalcemic hypoparathyroidism and hypokalemia, was reported in 64 individuals on long-term proton-pump inhibitors. Hypomagnesemia recurred following replacement of one proton-pump inhibitor with another but not with a histamine type-2 receptor antagonist. The association between proton-pump inhibitors and magnesium metabolism was addressed in 14 case-control, cross-sectional studies. An association was found in 11 of them: 6 reports found that the use of proton-pump inhibitors is associated per se with a tendency towards hypomagnesemia, 2 found that this tendency is more pronounced in patients concurrently treated with diuretics, carboplatin, or cisplatin, and 2 found a relevant tendency to hypomagnesemia in patients with poor renal function. Finally, findings likely reflecting decreased intestinal magnesium uptake were observed on treatment with proton-pump inhibitors. Three studies did not disclose any relationship between magnesium metabolism and treatment with histamine type-2 receptor antagonists. In conclusion, proton-pump inhibitors may cause hypomagnesemia. In these cases, switching to a histamine type-2 receptor antagonist is advised.

scholarly journals Hyperemesis-induced Wernicke-Korsakoff Syndrome due to Hypergastrinemia during Long-term Treatment with Proton Pump Inhibitors

2020 ◽  
Vol 59 (21) ◽  
pp. 2783-2787 ◽  
Author(s):  
Rei Miyanaga ◽  
Shin Hisahara ◽  
Ikkei Ohhashi ◽  
Daisuke Yamamoto ◽  
Akihiro Matsumura ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Term Treatment ◽  
Korsakoff Syndrome ◽  
Long Term Treatment

Severe Hypomagnesemia During Long-term Treatment With a Proton Pump Inhibitor

2010 ◽  
Vol 56 (1) ◽  
pp. 168-174 ◽  
Author(s):  
Giuseppe Regolisti ◽  
Aderville Cabassi ◽  
Elisabetta Parenti ◽  
Umberto Maggiore ◽  
Enrico Fiaccadori
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Term Treatment ◽  
Long Term Treatment
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