Quantitative analysis of cholesterol and cholesteryl esters in human atherosclerotic plaques using near-infrared Raman spectroscopy

1998 ◽  
Vol 140 (1) ◽  
pp. 81-88 ◽  
Author(s):  
Pierre Weinmann ◽  
Michel Jouan ◽  
Nguyen Quy Dao ◽  
Brigitte Lacroix ◽  
Corinne Groiselle ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Quantitative Analysis ◽  
Near Infrared ◽  
Atherosclerotic Plaques ◽  
Cholesteryl Esters

3.P.351 Determination of cholesterol content in human atherosclerotic plaques by near infrared Raman spectroscopy

1997 ◽  
Vol 134 (1-2) ◽  
pp. 272 ◽  
Author(s):  
P. Weinmann ◽  
G. Menard ◽  
B. Lacroix ◽  
L. Delaigue ◽  
M. Jouan ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Near Infrared ◽  
Cholesterol Content ◽  
Atherosclerotic Plaques ◽  
P 351

Quantitative Analysis of Cholesterol and Cholesterol Ester Mixtures Using Near-Infrared Fourier Transform Raman Spectroscopy

1996 ◽  
Vol 50 (10) ◽  
pp. 1253-1257 ◽  
Author(s):  
P. Le Cacheux ◽  
G. Menard ◽  
H. Nguyen Quang ◽  
P. Weinmann ◽  
M. Jouan ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Quantitative Analysis ◽  
Near Infrared ◽  
Quantitative Information ◽  
Ternary Mixtures ◽  
Synthetic Sample ◽  
Nondestructive Technique ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman

Near-infrared Fourier transform Raman spectroscopy is a rapid and nondestructive technique that can provide reliable qualitative in situ information about the chemistry of biological samples. We have combined this technique with partial least-squares (PLS) regression to perform a quantitative determination of free and esterified cholesterol in two synthetic sample series. In 66 ternary mixtures containing various proportions of cholesterol, cholesterol linoleate, and oleate, the standard errors of prediction were 1.27, 1.17, and 0.94%, respectively. For the second series of experiments concerning the sensitive problem of quantitative analysis of cholesterol palmitate and stearate mixtures, the standard error of prediction for 49 samples was 3.02%. It is also possible to extract quantitative information for a single component of the ternary mixtures independently. These results are of great importance when—as in the case of arterial samples—many chemical species are present. Comparison between Raman spectra of ternary mixtures and atherosclerotic rabbit aorta shows that many bands, assignable to free and esterified cholesterol, are easily observed in the aorta spectrum.

Use of Near-Infrared Raman Spectroscopy for Identification of Atherosclerotic Plaques in the Carotid Artery

2007 ◽  
Vol 25 (6) ◽  
pp. 482-486 ◽  
Author(s):  
Rick Rocha ◽  
Landulfo Silveira Jr. ◽  
Antonio Balbin Villaverde ◽  
Carlos A. Pasqualucci ◽  
Maricilia S. Costa ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Carotid Artery ◽  
Near Infrared ◽  
Atherosclerotic Plaques

Quantitative analysis of skin chemicals using rapid near-infrared Raman spectroscopy

2008 ◽  
Author(s):  
Jianhua Zhao ◽  
Zhiwei Huang ◽  
Haishan Zeng ◽  
David I. McLean ◽  
Harvey Lui
Keyword(s):  
Raman Spectroscopy ◽  
Quantitative Analysis ◽  
Near Infrared
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