scholarly journals Cytochrome P-450 of adrenal mitochondria. Steroid binding sites on two distinguishable forms of rat adrenal mitochondrial cytochrome P-450sec.

1977 ◽  
Vol 252 (24) ◽  
pp. 8788-8796 ◽  
Author(s):  
C.R. Jefcoate
Keyword(s):  
Binding Sites ◽  
Mitochondrial Cytochrome ◽  
Steroid Binding ◽  
Cytochrome P 450

scholarly journals 26-Hydroxylation of C27-steroids by soluble liver mitochondrial cytochrome P-450.

1979 ◽  
Vol 254 (14) ◽  
pp. 6464-6469 ◽  
Author(s):  
J I Pedersen ◽  
I Björkhem ◽  
J Gustafsson
Keyword(s):  
Mitochondrial Cytochrome ◽  
Cytochrome P 450

scholarly journals Affinity Labeling of Steroid Binding Sites

1971 ◽  
Vol 246 (11) ◽  
pp. 3646-3652 ◽  
Author(s):  
Manik Ganguly ◽  
James C. Warren
Keyword(s):  
Binding Sites ◽  
Affinity Labeling ◽  
Steroid Binding

Vitamin D-binding protein: multifunctional component of blood serum

2021 ◽  
Vol 76 (1) ◽  
pp. 103-110
Author(s):  
Alexandra A. Povaliaeva ◽  
Ekaterina A. Pigarova ◽  
Anastasia A. Romanova ◽  
Larisa K. Dzeranova ◽  
Artem Y. Zhukov ◽  
...  
Keyword(s):  
Vitamin D ◽  
Binding Sites ◽  
Binding Protein ◽  
Vitamin D Metabolites ◽  
Biological Functions ◽  
Vitamin D Binding Protein ◽  
Fatty Acid Binding ◽  
Physiological Properties ◽  
Steroid Binding ◽  
Tumor Pathogenesis

Vitamin D-binding protein (DBP) was discovered more than half a century ago as a polymorphic serum protein and is currently characterized by a variety of physiological properties. First of all, DBP carries the bulk of vitamin D metabolites circulating in the bloodstream, while albumin is the second most important transport protein, especially in patients with a low concentration of DBP in serum. Since it was discovered that only 12% of the total circulating DBP have occupied steroid binding sites, a vigorous study of other potential biological roles of DBP was initiated: actin utilization, regulation of inflammation and innate immunity mechanisms, fatty acid binding, effects on bone metabolism and participation in the tumor pathogenesis. This review focuses on the main known biological functions of DBP.

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