scholarly journals Structure of mouse submaxillary gland renin. Identification of two disulfide-linked polypeptide chains and the complete amino acid sequence of the light chain.

1982 ◽  
Vol 257 (13) ◽  
pp. 7536-7540 ◽  
Author(s):  
K S Misono ◽  
T Inagami
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Light Chain ◽  
Submaxillary Gland ◽  
Complete Amino Acid Sequence ◽  
Mouse Submaxillary Gland ◽  
Polypeptide Chains

Complete amino acid sequence and maturation of the mouse submaxillary gland renin precursor

Nature ◽  
1982 ◽  
Vol 298 (5869) ◽  
pp. 90-92 ◽  
Author(s):  
Jean-Jacques Panthier ◽  
Simon Foote ◽  
Béatrice Chambraud ◽  
A. Donny Strosberg ◽  
Pierre Corvol ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Submaxillary Gland ◽  
Complete Amino Acid Sequence ◽  
Mouse Submaxillary Gland

scholarly journals Amino acid sequence of mouse submaxillary gland renin.

1982 ◽  
Vol 79 (16) ◽  
pp. 4858-4862 ◽  
Author(s):  
K. S. Misono ◽  
J. J. Chang ◽  
T. Inagami
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Submaxillary Gland ◽  
Mouse Submaxillary Gland

Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as .beta.-hydroxyaspartic acid

Biochemistry ◽  
1983 ◽  
Vol 22 (12) ◽  
pp. 2875-2884 ◽  
Author(s):  
Brad A. McMullen ◽  
Kazuo Fujikawa ◽  
Walter Kisiel ◽  
Tatsuru Sasagawa ◽  
William N. Howald ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Blood Coagulation ◽  
Light Chain ◽  
Human Blood ◽  
Coagulation Factor ◽  
Factor X ◽  
Complete Amino Acid Sequence ◽  
Human Blood Coagulation

The complete amino acid sequence of rat submaxillary gland tonin does contain the aspartic acid at the active site: confirmation by protein sequence analyses

1987 ◽  
Vol 65 (4) ◽  
pp. 321-337 ◽  
Author(s):  
C. Lazure ◽  
R. Leduc ◽  
N. G. Seidah ◽  
G. Thibault ◽  
J. Genest ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Active Site ◽  
Serine Proteases ◽  
Submaxillary Gland ◽  
Catalytic Triad ◽  
Complete Amino Acid Sequence ◽  
Molecular Weights ◽  
Amino Acid Peptide ◽  
Close Relationship

The revised amino acid sequence of rat submaxillary gland tonin, a serine protease, does contain the active site Asp residue. The active site of this kallikrein-related enzyme is thus made up of the same catalytic triad (Asp, Ser, and His) found in all known serine proteases. The important Asp residue has now been localized in a 16 amino acid peptide previously reported as missing in the tonin sequence. The complete amino acid sequence thus contains 235 residues corresponding to a molecular weight of 25 658, more in agreement with previously reported molecular weights. Moreover, the revised structure led (a) to the assignment of Arg, Asn, and Val residues instead of His, Asp, and Gly at positions 63, 165, and 169, respectively; (b) to the assignment of residues occupying an overlapping sequence at positions 165–171, and finally (c) to the localization of two N-glycosylation sites at positions 82 and 165. These results further document the close relationship of tonin to the ever expanding kallikrein family.

Sign in / Sign up

Export Citation Format

Share Document