human blood coagulation
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2019 ◽  
Vol 7 (9) ◽  
pp. 200-212
Author(s):  
Abraham A. Embi Bs

The human blood coagulation cascade had been extensively researched from a biochemistry and molecular perspective. The purpose of this manuscript is to introduce a biophysical phenomenon detected via optical microscopy at the end of the human blood coagulation cascade. This could be described as a sudden energy event in the form of light radiation observed once blood tissue movement stops being attracted to metal iron filings or carbon based graphite particles used as sentinels. Upon close examination of video recordings, the sudden movements of iron particles images coincided with light at the end of the coagulation cascade. A literature search confirmed that both metal filings and graphite particles to possess excellent electrical conductivity. A biophysical light radiation event discharge is hypothesized as result of a burst in the conversion of fibrinogen to fibrin signaling the end of a coagulation cycle; perhaps combined with a piezoelectric effect induced by a sudden clumping of RBCs, or from the optical absorption or water. Method: Metal iron filings or graphite particles were randomly sprinkled on fresh TIBS preparations. The sample was then readily focused and selected particles chosen for video analysis. Equipment used was a video microscope Celestron Model # 44348, glass slides and author’s blood drops. The data was digitally transferred and stored in an Apple computer photo application for further review. Results: When metal iron filings or graphite particles were sprinkled on freshly prepared TIBS slides, video analysis show light radiation emitted at the end of the blood coagulation cascade. Discussion: Since the light radiation emission occurred at the end of the blood coagulation cycle, it is theorized that blood tissue compression could induce piezoelectricity coinciding with energy released by a fibrin burst, or by the optical absorption of water.


Author(s):  
N.S. Abegunasekara ◽  
A.M.A.G.K.S. Bandara

In most of the Ayurvedic remedies, Diospyros malabarica is used to obtain Rakthasthambana (coagulation) effect. The effect of leaves and stem bark extract of Diospyros malabarica on human blood coagulation was investigated using Lee and White method at Gampaha Wickramarachchi Ayurveda Institute in Sri Lanka. A total of 20 healthy individuals representing both sex were included in the study. For the test group, three tubes containing a volume of 0.5mL of stem bark extract were allocated, and the sap was replaced with normal saline for the tubes of the control group. A volume of 1mL of drawn blood was quickly added for every six tubes in situ, and all were incubated in a water bath at 37˚C. Every tube of two groups was observed carefully for a clot to measure the average clotting time of each group separately. Above procedure was repeated to all the fresh juice samples of stem bark and the leaves of Diospyros malabarica. The statistically significant reduction of average clotting time has proved that the stem bark of Diospyros malabarica and leaves of Diospyros malabarica have a highly significant effect on clotting cascade.


2019 ◽  
Vol 3 (3) ◽  
pp. 190012-0
Author(s):  
Quan Shen ◽  
Pengjie Tang ◽  
Ming Ma ◽  
Bin Bao

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