scholarly journals cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain specifically recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript.

1992 ◽  
Vol 267 (22) ◽  
pp. 15829-15835
Author(s):  
Z Liu ◽  
L.A. Diaz ◽  
A.L. Haas ◽  
G.J. Giudice
Keyword(s):  
Cdna Cloning ◽  
Pemphigus Foliaceus ◽  
Carrier Protein ◽  
Secondary Reading ◽  
Reading Frame ◽  
Human Ubiquitin ◽  
Endemic Pemphigus Foliaceus ◽  
Antigenic Domain

scholarly journals att, a target for regulation by tra2 in the testes of Drosophila melanogaster, encodes alternative RNAs and alternative proteins.

1996 ◽  
Vol 16 (8) ◽  
pp. 4222-4230 ◽  
Author(s):  
S J Madigan ◽  
P Edeen ◽  
J Esnayra ◽  
M McKeown
Keyword(s):  
Rna Processing ◽  
Transmembrane Domain ◽  
Somatic Tissue ◽  
Open Reading Frame ◽  
Graves Disease ◽  
Carrier Protein ◽  
Reading Frame ◽  
Protein Levels ◽  
Somatic Tissues ◽  
Promoter Usage

We have identified a gene, alternative testis transcripts (att), which is alternatively expressed, at both the RNA and protein levels, in testes and somatic tissues. The testis-specific RNA differs from somatic RNAs in both promoter usage and RNA processing and is dependent on the function of the transformer 2 gene. The differences between the somatic and testis RNAs have substantial consequences at the protein level. The somatic RNAs encode a protein with homology to the mammalian Graves' disease carrier proteins. The testis RNA lacks the initiation codons used in somatic tissue and encodes two different proteins. One of these begins in a testis-specific exon, uses a reading frame different from that for the somatic protein, and is completely novel. The other protein initiates translation in the frame of the somatic RNA at a Len CUG codon which is within the open reading frame for the somatic protein. This produces a novel truncated version of the Graves' disease carrier protein-like protein that lacks all sequences N terminal to the first transmembrane domain.

Analyses of autoantigens in a new form of endemic pemphigus foliaceus in Colombia

2003 ◽  
Vol 49 (4) ◽  
pp. 609-614 ◽  
Author(s):  
Ana María Abrèu-Velez ◽  
Ernst H Beutner ◽  
Fernando Montoya ◽  
Wendy B Bollag ◽  
Takashi Hashimoto
Keyword(s):  
Pemphigus Foliaceus ◽  
Endemic Pemphigus Foliaceus ◽  
New Form

scholarly journals T Cell Receptor β Chain Gene Usage in Endemic Pemphigus Foliaceus (Fogo Selvagem)

2002 ◽  
Vol 119 (2) ◽  
pp. 377-383 ◽  
Author(s):  
Achim K. Moesta ◽  
Animesh A. Sinha ◽  
Mong-Shang Lin ◽  
Luis A. Diaz
Keyword(s):  
T Cell ◽  
T Cell Receptor ◽  
Cell Receptor ◽  
Chain Gene ◽  
Pemphigus Foliaceus ◽  
Gene Usage ◽  
Endemic Pemphigus Foliaceus ◽  
Β Chain
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