Quality of Life Is Impaired in Men With Chronic Prostatitis. The Chronic Prostatitis Collaborative Research Network

Background: Chronic prostatitis/chronic pelvic pain syndrome (IIIB CP/CPPS) is a condition of unclear aetiology. Many approaches have been used without satisfactory results. The aim of this study is to evaluate the efficacy of once-daily 5 mg tadalafil in pain control and improving quality of life in patients affected by CP/CPPS. Methods: Twenty patients affected by chronic prostatitis according EAU (European Association of Urology) guidelines were evaluated for once-daily 5 mg tadalafil; 14 patients were eligible for the study. The validated Italian version of the NIH Chronic Prostatitis Symptom Index (NIH-CPSI) and the International Prostatic Symptom Score (IPSS) questionnaires were submitted to all the patients. Every patient underwent uroflowmetry and ultrasound prostatic volume at the beginning and at the end of the study. Results: All 14 patients eligible for the study reported an improvement of symptoms during therapy: statistically significant differences were reported in terms of NIH-CPSI ( p < 0.000002) and IPSS ( p < 0.0001) during follow-up evaluations. No statistically significant improvement of uroflowmetry parameters was reported during the treatment. Conclusions: In our study the daily use of 5 mg tadalafil improves symptoms and quality of life in patients affected by CP/CPPS after 4 weeks of therapy. A larger population of patients is needed to confirm the efficacy of this therapy in CP/CPPS.

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Quality of life is impaired in men with chronic prostatitis

Journal of General Internal Medicine ◽

10.1111/j.1525-1497.2001.01223.x ◽

2001 ◽

Vol 16 (10) ◽

pp. 656-662 ◽

Cited By ~ 178

Author(s):

Mary McNaughton Collins ◽

◽

Michel A. Pontari ◽

Michael P. O’Leary ◽

Elizabeth A. Calhoun ◽

...

Keyword(s):

Quality Of Life ◽

Chronic Prostatitis

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Urban virtues and the innovative city: An experiment in placing innovation in Edmonton, Canada

Urban Studies ◽

10.1177/0042098017719191 ◽

2017 ◽

Vol 56 (4) ◽

pp. 705-721 ◽

Cited By ~ 1

Author(s):

Kevin Edson Jones ◽

Michael Granzow ◽

Rob Shields

Keyword(s):

Quality Of Life ◽

Research Methodology ◽

Collaborative Research ◽

Innovation Strategy ◽

Citizen Engagement ◽

Local Identities ◽

Development Goals ◽

The City

In the highly competitive landscape of global cities and entrepreneurial urbanism, the development goals of cities are increasingly framed through discourses of ‘innovation’. In this paper we critically examine this relationship through a case study exploring the attempt to build a nanotechnology sector in Edmonton, Alberta. Adopting a collaborative research methodology involving citizen engagement and urban touring, we explore participant representations of Edmonton as an ‘innovative city’. The conversations we had with participants follow some common themes within an emerging literature on innovation geographies, for instance as related to network collaborations and quality of life. However, participants furthermore articulated innovation pathways which were more closely linked to local identities and values within the city, including negative place narratives. We argue that paying attention to these ‘virtues of place’ can assist cities to counteract trends towards the homogenisation of urban innovation strategy, and affix the ‘innovative city’ to more socially robust articulations of the future prosperity and the possibility of place.

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The association of Boswellia resin extract and propolis derived polyphenols can improve quality of life in patients affected by prostatitis-like symptoms

Archivio Italiano di Urologia e Andrologia ◽

10.4081/aiua.2019.4.251 ◽

2020 ◽

Vol 91 (4) ◽

pp. 251-255 ◽

Cited By ~ 1

Author(s):

Mattia Sibona ◽

Paolo Destefanis ◽

Marco Agnello ◽

Beatrice Lillaz ◽

Mattia Giuliano ◽

...

Keyword(s):

Quality Of Life ◽

Adverse Events ◽

Chronic Prostatitis ◽

Life Domain ◽

Domain Score ◽

Improve Quality ◽

Symptom Index ◽

Resin Extract ◽

Pain Domain

Objectives: Chronic prostatitis syndrome is a bothering and poorly understood condition. Many patients report genitourinary pain and Lower Urinary Tract Symptoms as a main complaint. Many different pharmacological or behavioural therapies are prescribed in daily clinical practice, but efficacy data are still lacking. The aim of our study was to test the efficacy and safety of a transrectal delivered association of Boswellia resin extract and propolis derived polyphenols for the relief of prostatitis - like symptoms. Materials and methods: Patients affected by chronic/recurrent prostatitis - like symptoms were prospectively enrolled in our study from December, 2016 to December, 2018. Patients were screened at baseline through clinical examination and validated questionnaires administration: Chronic Prostatitis Symptom Index (CPSI), International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF). Inclusion criteria were: age ≥ 18; prostatitis symptoms persisting for at least 3 of the last 6 months; CPSI pain domain score ≥ 5; previous negative Meares-Stamey test. Treatment consisted on the administration of 1 suppository containing Boswellia resin extract and propolis derived polyphenols, once a day for 20 days. The primary endpoint of the study was the improvement of quality of life after treatment, defined by a reduction of ≥ 2 points, or ≥ 25%, of mean CPSI pain domain score, compared to baseline. Secondary endpoints were the improvement of post-treatment CPSI total score and the analysis of treatment - related adverse events. All patients were re-evaluated 1 month after treatment. Results: 40 patients were enrolled in our study. Median age (Inter - Quartile Range IQR) was 51.5 (41.5-63.2) years. Mean baseline CPSI scores were: 22.15 (total score), 9.67 (pain domain), 5.15 (micturition domain) and 7.35 (quality of life domain), respectively. No significant adverse events were reported. At 1 month follow-up, CPSI scores appeared modified as follows: 16.40 (total score, p = 0.001); 6.92 (pain domain; p = 0.001; 4.02 (micturition domain, p = 0.09); 5.45 (quality of life domain, p = 0.002). Mean CPSI pain domain score reduction was -2.75 points (-28.5%). Mean CPSI total score reduction was -5.75 points (-26%). Conclusions: The association of Boswellia resin extract and propolis derived polyphenols can reduce genitourinary pain and then improve quality of life of men affected by bothersome prostatitis - like symptoms.

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P.136 Quantifying potential sources of delay in surgical management of cervical spondylotic myelopathy

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/cjn.2018.238 ◽

2018 ◽

Vol 45 (s2) ◽

pp. S52-S52

Author(s):

V Chan ◽

A Nataraj

Keyword(s):

Quality Of Life ◽

Cervical Spondylotic Myelopathy ◽

Short Form ◽

Research Network ◽

Physical Component Score ◽

Decompression Surgery ◽

Duration Of Symptoms ◽

Component Score

Background: Cervical spondylotic myelopathy is a degenerative condition with a variable clinical course. We aim to quantify the sources of potential delay in management and understand how the timing of these events may affect quality of life measures. Methods: The Canadian Spine Outcomes Research Network Registry was used to identify patients older than 18 years of age and have received cervical decompression surgery from January 1, 2013 to March 1, 2016. The primary outcome was the Short Form-12 Physical Component Score at 12-month follow-up. Four time groups were identified: 1) duration of symptoms, 2) time awaiting surgical consult, 3) time spent monitoring symptoms, and 4) time awaiting surgery. -Multivariate regression was used for analysis. Results: A total of 208 patients were identified. The mean age was 59.5 years. 61.53% of patients had symptoms for >12 months at initial consult. Mean time awaiting surgical consult, monitoring symptoms, and awaiting surgery was 77.2, 60.9, and 46.9 days, respectively. Time awaiting surgery (β=-0.032, p=0.04) was a significant factor for change in Physical Component Score. Conclusions: We found time awaiting surgery to be a significant factor on PSC score at 12-month follow-up. Increased time awaiting surgery may result in negative impacts on quality of life outcomes.

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“Running Water Won't Freeze”: How people with advanced Parkinson's disease experience occupation

Palliative & Supportive Care ◽

10.1017/s1478951514001357 ◽

2014 ◽

Vol 13 (5) ◽

pp. 1363-1372 ◽

Cited By ~ 10

Author(s):

Carolyn Murdock ◽

Wendy Cousins ◽

W. George Kernohan

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Palliative Care ◽

Parkinson's Disease ◽

Occupational Therapy ◽

Research Network ◽

Daily Lives ◽

Advanced Parkinson’S Disease ◽

Disease Experience

AbstractObjective:Parkinson's disease (PD) is a progressive neurodegenerative condition often resulting in significant disability and impacting on one's ability to participate in an occupation. The present study aimed to explore how people with advanced Parkinson's disease experience the phenomenon of occupation in their daily lives in order to inform the practice of occupational therapy in palliative care.Method:Using a phenomenological approach, in-depth interviews were undertaken with a purposive sample of 10 people in the advanced stages of Parkinson's disease. These interviews were audiotaped, transcribed verbatim, and subsequently analyzed using a thematic content analysis approach. The study received approval from the relevant university ethics committee, as well as the research network of Parkinson's UK.Results:The experience of occupation emerged as being physical, psychological, social, and spiritual with related subthemes. Within each of these themes, participants described their experience of occupation that they valued and that were important to their daily lives. They also identified the strategies they employed to continue participating in certain occupations and described others they were no longer able to engage in and the impact of that loss.Significance of Results:Participants' experiences crossed the domains of palliative care and suggest that adopting a palliative care approach would enhance an enhanced quality of life, experienced in terms of meaningful and valuable occupation. Disruption to participation in occupation caused them distress and frustration, suggesting that access to occupation-focused therapy would significantly improve quality of life for people with PD. As there is a strong link between the ethos of occupational therapy and palliative care, it is proposed that there is a valuable role for occupational therapy intervention to play within palliative care.

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