WOCA, Botulinum Toxin Considered for Neurogenic Bladder

Ob Gyn News ◽  
2011 ◽  
Vol 46 (7) ◽  
pp. 14
Author(s):  
CHRISTINE KILGORE
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder

1125: Botulinum Toxin a in Neurogenic Bladder: Are there any Patient Predictors of Response?

2005 ◽  
Vol 173 (4S) ◽  
pp. 305-305
Author(s):  
Brigitte Schurch ◽  
Marianne de Seze ◽  
Pierre Denys ◽  
Emmanuel Chartier-Kastler ◽  
Francois Haab ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Botulinum Toxin A ◽  
Toxin A ◽  
Predictors Of Response

UP-03.169 Preserved Micturition in Parkinson Patients Treated With Botulinum Toxin for Neurogenic Bladder Dysfunction

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S400
Author(s):  
S. Knüpfer ◽  
K. Jünemann ◽  
M. Hamann
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Bladder Dysfunction ◽  
Neurogenic Bladder Dysfunction

scholarly journals Botulinum Toxin-A Therapy in Pediatric Urology: Indications for the Neurogenic and Non-Neurogenic Neurogenic Bladder

2009 ◽  
Vol 9 ◽  
pp. 1300-1305 ◽  
Author(s):  
Lori Dyer ◽  
Israel Franco
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Botulinum Toxin A ◽  
Sensory Nerve ◽  
Nerve Fibers ◽  
Review Article ◽  
Pediatric Urology ◽  
Urethral Sphincter ◽  
Toxin A

Although, the role of Botulinum Toxin-A in the treatment of the neurogenic and non-neurogenic neurogenic bladder is becoming more defined, this is the first review article to characterize the emerging role of Botulinum Toxin-A in the pediatric urologic population. Injection of Botulinum Toxin-A at the level of the bladder works by inhibiting uninhibited bladder contractions and, possibly, by blocking some of the sensory nerve fibers. In children with sphincter dyssynergy, injection at the level of the urethral sphincter works by inhibiting the involuntary guarding reflex and blocking dyssynergic voiding.

Repeated Injection of Botulinum Toxin a in Patients with Neurogenic Bladder: Our Experience

2012 ◽  
Vol 79 (19_suppl) ◽  
pp. 9-14
Author(s):  
Ubaldo Cantoro ◽  
Daniele Minardi ◽  
Vito Lacetera ◽  
Alessandro Conti ◽  
Francesco Catanzariti ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Botulinum Toxin A ◽  
Repeated Injection ◽  
Toxin A

Botulinum Toxin Injections to Treat Neurogenic Bladder — Sphincter Dysfunction in Pediatric Patients

2006 ◽  
pp. 199-202
Author(s):  
Brigitte Schurch ◽  
Gilles Karsenty ◽  
Jacques Corcos
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Pediatric Patients ◽  
Botulinum Toxin Injections

scholarly journals Effects of Botulinum Toxin Type A in the Bladder Wall of Children With Neurogenic Bladder Dysfunction: A Comparison of Histological Features Before and After Injections

2011 ◽  
Vol 185 (6S) ◽  
pp. 2552-2557 ◽  
Author(s):  
Maria Paola Pascali ◽  
Giovanni Mosiello ◽  
Renata Boldrini ◽  
Maria Letizia Salsano ◽  
Enrico Castelli ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Bladder Dysfunction ◽  
Botulinum Toxin Type A ◽  
Bladder Wall ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Neurogenic Bladder Dysfunction ◽  
Histological Features ◽  
Before And After

1657 PRESERVED MICTURITION IN PARKINSON PATIENTS TREATED WITH BOTULINUM TOXIN FOR NEUROGENIC BLADDER DYSFUNCTION

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Stephanie Knuüpfer ◽  
MOritz Hamann ◽  
Klaus-Peter Juünemann
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Bladder Dysfunction ◽  
Neurogenic Bladder Dysfunction

scholarly journals Efficacy and Safety of Botulinum Toxin A for Treating Bladder Hyperactivity in Children and Adolescents with Neuropathic Bladder Secondary to Myelomeningocele

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Antonio Marte ◽  
Micaela Borrelli ◽  
Maurizio Prezioso ◽  
Lucia Pintozzi ◽  
Pio Parmeggiani
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Botulinum Toxin A ◽  
Invasive Procedure ◽  
Bladder Capacity ◽  
Rank Test ◽  
Clean Intermittent Catheterization ◽  
Efficacy And Safety ◽  
Average Increase ◽  
Toxin A

We verified the efficacy and safety of botulinum toxin A (BTX-A) in treating bladder overactivity in children with neurogenic bladder (NB) secondary to myelomeningocele (MMC). Forty-seven patients (22, females; 25, males; age range, 5–17 years; mean age, 10.7 years) with poorly compliant/overactive neurogenic bladder on clean intermittent catheterization (CIC) and resistance or noncompliant to anticholinergics were injected with 200 IU of BTX-A intradetrusor. All patients experienced a significant 66.45% average increase of leak point volume (Wilcoxon paired rank test = 7.169 e-10) and a significant 118.57% average increase of specific bladder capacity at 20 cm H2O (Wilcoxon paired rank test = 2.466 e-12). Ten patients who presented with concomitant uni/bilateral grade II–IV vesicoureteral reflux were treated at the same time with Deflux. No patient presented with major perioperative or postoperative problems. Twenty-two patients needed a second and 18 a third injection of BTX-A after 6–9 months for the reappearance of symptoms. After a mean follow-up of 5.7 years, 38 out of 47 patients achieved dryness between CICs, and 9 patients improved their incontinence but still need pads. Our conclusion is that BTX-A represents a viable alternative to more invasive procedure in treatment of overactive NB secondary to MMC.

What is the optimum dose of type A botulinum toxin for treating neurogenic bladder overactivity?

2006 ◽  
Vol 97 (5) ◽  
pp. 1030-1034 ◽  
Author(s):  
ALAIN RUFFION ◽  
OLIVIER CAPELLE ◽  
PHILIPPE PAPAREL ◽  
BEATRICE LERICHE ◽  
ALBERT LERICHE ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Type A ◽  
Optimum Dose

Botulinum toxin A for neurogenic bladder?

2002 ◽  
Vol &NA; (1337) ◽  
pp. 18
Author(s):  
&NA;
Keyword(s):  
Botulinum Toxin ◽  
Neurogenic Bladder ◽  
Botulinum Toxin A ◽  
Toxin A
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