Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2

2002 ◽  
Vol 61 (7) ◽  
pp. 867-872 ◽  
Author(s):  
Dae Sik Jang ◽  
Muriel Cuendet ◽  
Michael E. Hawthorne ◽  
Leonardus B.S. Kardono ◽  
Kazuko Kawanishi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Cyclooxygenase 2 ◽  
Prenylated Flavonoids

Neolignans from North American Magnolia Species with Cyclooxygenase 2 Inhibitory Activity

2009 ◽  
Vol 17 (2) ◽  
pp. 106-110 ◽  
Author(s):  
W. Schühly ◽  
S. I. Khan ◽  
N. H. Fischer
Keyword(s):  
North American ◽  
Inhibitory Activity ◽  
Cyclooxygenase 2

Synthesis and Selective Cyclooxygenase-2 Inhibitory Activity of a Series of Novel, Nitric Oxide Donor-Containing Pyrazoles†

2004 ◽  
Vol 47 (9) ◽  
pp. 2180-2193 ◽  
Author(s):  
Ramani R. Ranatunge ◽  
Michael Augustyniak ◽  
Upul K. Bandarage ◽  
Richard A. Earl ◽  
James L. Ellis ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Cyclooxygenase 2 ◽  
Nitric Oxide Donor

Two new prenylated flavonoids from the seeds of Psoralea corylifolia with their inhibitory activity on α-glucosidase

2020 ◽  
Vol 39 ◽  
pp. 64-67
Author(s):  
Wen-Ting Fei ◽  
Jian-Jun Zhang ◽  
Ru-Ying Tang ◽  
Na Yue ◽  
Xue Zhou ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Psoralea Corylifolia ◽  
Prenylated Flavonoids

ChemInform Abstract: Prenylated Flavonoids with PTP1B Inhibitory Activity from the Root Bark of Erythrina mildbraedii.

ChemInform ◽  
2008 ◽  
Vol 39 (28) ◽  
Author(s):  
JunPil Jang ◽  
MinKyun Na ◽  
Phuong Thien Thuong ◽  
Dieudonne Njamen ◽  
Joseph Tanyi Mbafor ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Root Bark ◽  
Prenylated Flavonoids

scholarly journals 2-Amino-5-sulfanyl-1,3,4-thiadiazoles: A new series of selective cyclooxygenase-2 inhibitors

2008 ◽  
Vol 58 (3) ◽  
pp. 317-326 ◽  
Author(s):  
Rajesh Sharma ◽  
Jitendra Sainy ◽  
Subhash Chaturvedi
Keyword(s):  
Biological Activity ◽  
Spectral Methods ◽  
Inhibitory Activity ◽  
Cyclooxygenase 2 ◽  
Tail Flick ◽  
Screening Assay ◽  
Paw Oedema ◽  
Rat Paw ◽  
Cyclooxygenase 2 Inhibitors ◽  
Rat Paw Oedema

2-Amino-5-sulfanyl-1,3,4-thiadiazoles: A new series of selective cyclooxygenase-2 inhibitorsA new series of cyclooxygenase-2 inhibitors with 2-amino--5-sulfanyl-1,3,4-thiadiazole as the central scaffold unit has been synthesized. The newly synthesized compounds were characterized by analytical and spectral methods. Compounds were screened for cyclooxygenase inhibitory activity by the colorimetric COX (ovine) inhibitor screening assay, anti-inflammatory activity by the carrageenean induced rat paw oedema test and analgesic activity by the tail flick method. Some compounds exhibited significant biological activity.

Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles

2004 ◽  
Vol 12 (6) ◽  
pp. 1357-1366 ◽  
Author(s):  
Ramani R. Ranatunge ◽  
David S. Garvey ◽  
David R. Janero ◽  
L.Gordon Letts ◽  
Allison M. Martino ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Cyclooxygenase 2 ◽  
Cox 2

CYCLOOXYGENASE-2 AS „IN SILICO“ TARGET OF PHENOLIC HYDRAZONE- TYPE DERIVATIVES

2021 ◽  
Author(s):  
Jovica Branković ◽  
◽  
Vesna Milovanović ◽  
Vladimir P. Petrović
Keyword(s):  
Inhibitory Activity ◽  
In Silico ◽  
Cyclooxygenase 2 ◽  
Inflammation Mediators ◽  
Biological Features ◽  
Cox 2

In the present work, a series of phenolic hydrazone analogs were investigated in silico for their potential inhibitory activity toward COX-2. These examinations were based on the capability of hydrazone-based compounds to interact with numerous enzymes, as well as on their versatile biological features and therapeutical applications. COX-2 was selected due to its involvement in the inflammation and carcinogenesis processes. Regarding this, COX-2 represents a valid target for the development of compounds that could block the formation of harmful inflammation mediators.

Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity

2015 ◽  
Vol 25 (17) ◽  
pp. 3455-3457 ◽  
Author(s):  
Yang Hee Jo ◽  
Seon Beom Kim ◽  
Qing Liu ◽  
Jin Woo Lee ◽  
Bang Yeon Hwang ◽  
...  
Keyword(s):  
Pancreatic Lipase ◽  
Inhibitory Activity ◽  
Cudrania Tricuspidata ◽  
Prenylated Flavonoids
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