Two Plaque-Size Variants of Foot-and-Mouth Disease Virus Differing in Neutralization by Guinea-Pig Antisera

1971 ◽  
Vol 12 (4) ◽  
pp. 399-400 ◽  
Author(s):  
J.S. Martinsen
Keyword(s):  
Guinea Pig ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Plaque Size ◽  
Mouth Disease Virus ◽  
Foot And Mouth

scholarly journals The specific detection of foot-and-mouth disease virus whole particle antigen (140S) by enzyme labelled immunosorbent assay

1979 ◽  
Vol 83 (1) ◽  
pp. 127-134 ◽  
Author(s):  
E. M. E. Abu Elzein ◽  
J. R. Crowther
Keyword(s):  
Guinea Pig ◽  
Disease Virus ◽  
Immunosorbent Assay ◽  
Solid Phase ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Specific Detection ◽  
Sandwich Technique ◽  
Mouth Disease Virus ◽  
Foot And Mouth

SUMMARYA solid-phase micro-enzyme-labelled immunosorbent assay (ELISA) using guinea pig antiserum against purified (140S) inactivated foot-and-mouth disease (FMD) virus has been usedin a sandwich technique to specifically measure 140S virus in the presence of 12S material.

A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds

2014 ◽  
Vol 63 (2) ◽  
pp. e205-e212 ◽  
Author(s):  
A. R. De Vleeschauwer ◽  
D. J. Lefebvre ◽  
T. Willems ◽  
G. Paul ◽  
A. Billiet ◽  
...  
Keyword(s):  
Virus Infection ◽  
Guinea Pig ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Pig Model ◽  
Antiviral Compounds ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Guinea Pig Model

scholarly journals Replication and attenuation of foot and mouth disease virus in chick embryo

2012 ◽  
Vol 9 (1) ◽  
pp. 31-35
Author(s):  
Baghdad Science Journal
Keyword(s):  
Tissue Culture ◽  
Chick Embryo ◽  
Guinea Pig ◽  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Challenge Virus ◽  
Mouth Disease Virus ◽  
Attenuated Virus ◽  
Foot And Mouth

This study includes replication and attenuation of foot and mouth disease virus type O which isolated from infected calves. Many passages for the virus in chick-Embryo were established as a substitute method to the tissue culture which is highly caustic in contrast to the chick embryo. The virus passed ten consequent passages which lead to the reduce of the titer of the virus from 106.53 TCID50/ 0.1 ml in cattle testis tissue culture to 103 TCID50/ 0.1 ml. the pathogenecity of attenuated FMD virus were also studied in both chick-embryo and guinea pigs. Using agar gel diffusion test precipitation antibodies was detected in guinea pig serum after 14 and 21 days post exposure to the attenuated virus. The inoculated guinea pig group with the chick-embryo attenuated virus appear resistance to the challenge virus. The result suggested the efficacy of attenuation of foot and mouth disease virus by using chick-embryo system for immunization against this disease on the level of laboratory Animal.

Sign in / Sign up

Export Citation Format

Share Document