Asymmetric alkylation reaction of α-fluorotetralone under phase-transfer catalyzed conditions

1999 ◽  
Vol 40 (37) ◽  
pp. 6785-6789 ◽  
Author(s):  
Shigeru Arai ◽  
Makoto Oku ◽  
Toshimasa Ishida ◽  
Takayuki Shioiri
Keyword(s):  
Phase Transfer ◽  
Alkylation Reaction ◽  
Asymmetric Alkylation

ChemInform Abstract: Asymmetric Alkylation Reaction of α-Fluorotetralone under Phase-Transfer Catalyzed Conditions.

ChemInform ◽  
2010 ◽  
Vol 30 (47) ◽  
pp. no-no
Author(s):  
Shigeru Arai ◽  
Makoto Oku ◽  
Toshimasa Ishida ◽  
Takayuki Shioiri
Keyword(s):  
Phase Transfer ◽  
Alkylation Reaction ◽  
Asymmetric Alkylation

scholarly journals A Remarkably Efficient Phase-Transfer Catalyzed Amination of α-Bromo-α, β-Unsaturated Ketones in Water

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Alemayehu Mekonnen ◽  
Alemu Tesfaye
Keyword(s):  
Quaternary Ammonium ◽  
Phase Transfer ◽  
Conjugate Addition ◽  
Quaternary Ammonium Salts ◽  
Cinchona Alkaloids ◽  
Ammonium Salts ◽  
Alkylation Reaction ◽  
Pt Catalysts ◽  
Unsaturated Ketones ◽  
Catalytic Performances

Tandem conjugate addition–alkylation reaction of various amines with α-bromo-α, β-unsaturated ketones resulted in near-quantitative conversions into the corresponding aziridines when the reaction was carried out in the presence of 10 mol% of phase-transfer, PT catalysts in water. Some chiral quaternary ammonium salts derived from Cinchona alkaloids were investigated as water-stable PT catalysts. The scope and limitations of the reaction have also been investigated. The catalytic performances were significantly improved in comparison with the corresponding ordinary quaternary ammonium salt catalysts, and excellent yields (81%–96%) were obtained. Although an increase in the rate of aziridination has been accomplished, no stereoselectivity was observed. The positive values of the protocol have been confirmed.

The mechanism of phase transfer in the O-alkylation reaction of diols

2008 ◽  
Vol 48 (6) ◽  
pp. 434-439
Author(s):  
N. V. Morozova ◽  
N. N. Lebedeva ◽  
L. P. Panicheva
Keyword(s):  
Phase Transfer ◽  
Alkylation Reaction

scholarly journals Highly Enantioselective Construction of Quaternary Stereocenters onβ-Keto Esters by Phase-Transfer Catalytic Asymmetric Alkylation and Michael Reaction

2003 ◽  
Vol 115 (34) ◽  
pp. 4111-4111 ◽  
Author(s):  
Takashi Ooi ◽  
Takashi Miki ◽  
Mika Taniguchi ◽  
Misato Shiraishi ◽  
Mifune Takeuchi ◽  
...  
Keyword(s):  
Michael Reaction ◽  
Phase Transfer ◽  
Asymmetric Alkylation ◽  
Keto Esters ◽  
Catalytic Asymmetric ◽  
Quaternary Stereocenters
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