Chapter 4 Signal Transduction by GTP Binding Proteins during Leukocyte Activation: Phagocytic Cells

1990 ◽  
pp. 65-101 ◽  
Author(s):  
Gary M. Bokoch
Keyword(s):  
Signal Transduction ◽  
Binding Proteins ◽  
Leukocyte Activation ◽  
Phagocytic Cells ◽  
Gtp Binding Proteins ◽  
Gtp Binding

Small molecular weight GTP-binding proteins and signal transduction

1989 ◽  
Vol 185 (3) ◽  
pp. 347-355 ◽  
Author(s):  
Katsuhiko Yamamoto ◽  
Tetsuji Tanimoto ◽  
Shigekuni Kim ◽  
Akira Kikuchi ◽  
Yoshimi Takai
Keyword(s):  
Signal Transduction ◽  
Molecular Weight ◽  
Binding Proteins ◽  
Small Molecular Weight ◽  
Gtp Binding Proteins ◽  
Gtp Binding

Cellular responses regulated by rho-related small GTP-binding proteins

1993 ◽  
Vol 340 (1293) ◽  
pp. 267-271 ◽  
Keyword(s):  
Plasma Membrane ◽  
Binding Proteins ◽  
Focal Adhesions ◽  
Receptor Activation ◽  
Small Gtpases ◽  
Membrane Receptors ◽  
Phagocytic Cells ◽  
Gtp Binding Proteins ◽  
Gtp Binding ◽  
Plasma Membrane Receptors

Rho-related proteins are members of the ras superfamily of small GTP-binding proteins. Their function in fibroblasts has been analysed using microinjection of living cells. Rho appears to link plasma membrane receptors to the assembly of focal adhesions and actin stress fibres. The closely related protein rac, on the other hand, links receptors to the polymerization of actin at the plasma membrane to form membrane ruffles and pinocytotic vesicles. In phagocytic cells, rac has been shown to be required for activation of a membrane-bound NADPH oxidase in response to receptor activation. These systems provide the basis for a working model for the mechanism of action of the rho family of small GTPases.

GTP-binding Proteins and Signal Transduction

2009 ◽  
pp. 81-129
Author(s):  
Bastien D. Gomperts ◽  
IJsbrand M. Kramer ◽  
Peter E.R. Tatham
Keyword(s):  
Signal Transduction ◽  
Binding Proteins ◽  
Gtp Binding Proteins ◽  
Gtp Binding
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