Radioiodine Ablation of Thyroid Remnants after Preparation with Recombinant Human Thyrotropin in Differentiated Thyroid Carcinoma: Results of an International, Randomized, Controlled Study

2007 ◽  
Vol 2007 ◽  
pp. 267-269
Author(s):  
E.L. Mazzaferri
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled ◽  
Radioiodine Ablation ◽  
Recombinant Human Thyrotropin

scholarly journals Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Patients with Metastatic Differentiated Thyroid Carcinoma

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Ivana Zagar ◽  
Andreja A. Schwarzbartl-Pevec ◽  
Barbara Vidergar-Kralj ◽  
Rika Horvat ◽  
Nikola Besic
Keyword(s):  
Thyroid Carcinoma ◽  
Total Thyroidectomy ◽  
Physical Condition ◽  
Radioiodine Therapy ◽  
Differentiated Thyroid Carcinoma ◽  
Therapeutic Benefit ◽  
The Poor ◽  
Radioiodine Ablation ◽  
Recombinant Human Thyrotropin ◽  
Tsh Stimulation

Our aim was to test the efficacy of 131-I therapy (RIT) using recombinant human TSH (rhTSH) in patients with differentiated thyroid carcinoma (DTC) in whom endogenous TSH stimulation was not an option due to the poor patient's physical condition or due to the disease progression during L-thyroxin withdrawal. The study comprised 18 patients, who already have undergone total or near-total thyroidectomy and radioiodine ablation and 0–12 (median 5) RITs after L-thyroxin withdrawal. Our patients received altogether 44 RITs using rhTSH while on L-thyroxin. Six to 12 months after the first rhTSH-aided RIT, PR and SD was achieved in 3/18 (17%) and 4/18 patients (22%), respectively. In most patients (n= 12; 61%) disease progressed despite rhTSH-aided RITs. As a conclusion, rhTSH-aided RIT proved to add some therapeutic benefit in 39% our patients with metastatic DTC, who otherwise could not be efficiently treated with RIT.

Foreign language learning in older age does not improve memory or intelligence: Evidence from a randomized controlled study.

2020 ◽  
Vol 35 (2) ◽  
pp. 212-219
Author(s):  
Rasmus Berggren ◽  
Jonna Nilsson ◽  
Yvonne Brehmer ◽  
Florian Schmiedek ◽  
Martin Lövdén
Keyword(s):  
Foreign Language ◽  
Language Learning ◽  
Foreign Language Learning ◽  
Older Age ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled
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