Predictors of Mortality and Limb Loss in Necrotizing Soft Tissue Infections

2006 ◽  
Vol 2006 ◽  
pp. 129-131
Author(s):  
T.L. Pruett
Keyword(s):  
Soft Tissue ◽  
Limb Loss ◽  
Soft Tissue Infections ◽  
Predictors Of Mortality ◽  
Necrotizing Soft Tissue Infections

Necrotizing Soft-Tissue Infections in the Feet of Patients With Diabetes: Outcome of Surgical Treatment and Factors Associated With Limb Loss and Mortality

2009 ◽  
Vol 8 (3) ◽  
pp. 141-146 ◽  
Author(s):  
Javier Aragón-Sánchez ◽  
Yurena Quintana-Marrero ◽  
Jose L. Lázaro-Martínez ◽  
Maria J. Hernández-Herrero ◽  
Esther García-Morales ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Soft Tissue ◽  
Limb Loss ◽  
Soft Tissue Infections ◽  
Factors Associated ◽  
Patients With Diabetes ◽  
Necrotizing Soft Tissue Infections ◽  
Diabetes Outcome

Predictors of Mortality and Limb Loss in Necrotizing Soft Tissue Infections

2013 ◽  
Vol 79 (10) ◽  
pp. 1102-1105 ◽  
Author(s):  
Samuel Schwartz ◽  
Elizabeth Kightlinger ◽  
Christian De Virgilio ◽  
Michael De Virgilio ◽  
Amy Kaji ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Limb Loss ◽  
Therapeutic Interventions ◽  
Limb Amputation ◽  
Multivariable Logistic Regression Analysis ◽  
Soft Tissue Infections ◽  
Arterial Lactate ◽  
Necrotizing Soft Tissue Infections ◽  
Admission Variables

Necrotizing soft tissue infections (NSTIs) require prompt diagnosis and treatment. Early identification of patients at greatest risk of limb amputation and death may help in targeting aggressive medical and surgical management. The aim of this study was to assess predictors of limb loss and mortality in patients with NSTI based on admission variables. We performed a retrospective review of two hospitals that care for a large volume of patients with NSTI. Univariate and multi-variable analyses were used to determine the association of admission biochemical markers to limb loss and mortality. Of 174 patients with NSTI, there were 19 deaths (10.9%) and 42 required amputations (24.1%). Multivariable logistic regression analysis revealed that only arterial lactate was predictive for both mortality (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.1 to 2.0; P = 0.009) and limb loss (OR, 1.3; 95% CI, 1.0 to 1.7; P = 0.02). In patients with a suspected NSTI, an arterial lactate should be ordered early on to guide aggressive therapeutic interventions and to provide information with regard to long-term outcomes of amputation and death that is needed for early discussion with the patient and family.

Hyperbaric oxygen therapy as an adjuvant to source control in necrotizing soft tissue infections

2017 ◽  
Vol 44 (6) ◽  
pp. 535-542
Author(s):  
António Pedro Pinto Ferreira ◽  
◽  
Sérgio Santos Vide ◽  
Tiago David Fonseca Fernandes ◽  
Pedro Miguel Barata de Silva Coelho ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Source Control ◽  
Soft Tissue Infections ◽  
Necrotizing Soft Tissue Infections

Effect of transfer status on outcomes for necrotizing soft tissue infections

2017 ◽  
Vol 220 ◽  
pp. 372-378 ◽  
Author(s):  
Angela M. Ingraham ◽  
Hee Soo Jung ◽  
Amy E. Liepert ◽  
Charles Warner-Hillard ◽  
Caprice C. Greenberg ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Infections ◽  
Necrotizing Soft Tissue Infections
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