Protective role of a recombinant fragment of human surfactant protein D (SP-D) against pulmonary hypersensitivity in a murine model of dust mite allergy

2003 ◽  
Vol 111 (2) ◽  
pp. S199
Author(s):  
M.K. Singh ◽  
T.M. Gupta ◽  
B.C. Urban ◽  
U.P. Sarma ◽  
U. Kishore
2001 ◽  
Vol 69 (4) ◽  
pp. 2728-2731 ◽  
Author(s):  
Taruna Madan ◽  
Uday Kishore ◽  
Mamta Singh ◽  
Peter Strong ◽  
Ejaj M. Hussain ◽  
...  

ABSTRACT The protective effects of intranasal administration of amphotericin B (AmB), human SP-A, SP-D and a 60-kDa fragment of SP-D (rSP-D) were examined in a murine model of invasive pulmonary aspergillosis (IPA). The untreated group of IPA mice showed no survival at 7 days postinfection. Treatment with AmB, SP-D, and rSP-D increased the survival rate to 80, 60, and 80%, respectively, suggesting that SP-D (and rSP-D) can protect immunosuppressed mice from an otherwise fatal challenge with Aspergillus fumigatus conidia.


2003 ◽  
Vol 86 (3) ◽  
pp. 299-307 ◽  
Author(s):  
Mamta Singh ◽  
Taruna Madan ◽  
Patrick Waters ◽  
Shreemanta K. Parida ◽  
P.Usha Sarma ◽  
...  

1994 ◽  
Vol 94 (1) ◽  
pp. 311-319 ◽  
Author(s):  
K L Hartshorn ◽  
E C Crouch ◽  
M R White ◽  
P Eggleton ◽  
A I Tauber ◽  
...  

2018 ◽  
Author(s):  
Vasanthi R Sunil ◽  
Kinal N Vayas ◽  
Jessica A Cervelli ◽  
Elena V Ebramova ◽  
Andrew J Gow ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138597 ◽  
Author(s):  
Zhiyong Zhang ◽  
Osama Abdel-Razek ◽  
Samuel Hawgood ◽  
Guirong Wang

Pneumologie ◽  
2014 ◽  
Vol 68 (06) ◽  
Author(s):  
J Viereck ◽  
L Knudsen ◽  
JP Schneider ◽  
M Ochs ◽  
T Thum

Author(s):  
Walter Zin ◽  
Ana Gabriela Ledo Santos da Silva ◽  
Bernardo Pascarelli ◽  
Daniel Costa ◽  
Radovan Borojevic ◽  
...  
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