Contact allergy in chronic leg ulcers: results of a multicentre study carried out in 423 patients and proposal for an updated series of patch tests

2010 ◽  
Vol 2010 ◽  
pp. 116-117
Author(s):  
S. Bellew ◽  
J.Q. Del Rosso
2009 ◽  
Vol 60 (5) ◽  
pp. 279-287 ◽  
Author(s):  
Annick Barbaud ◽  
Evelyne Collet ◽  
Christophe J. Le Coz ◽  
Sylvie Meaume ◽  
Pierre Gillois

Medicina ◽  
2011 ◽  
Vol 47 (9) ◽  
pp. 480 ◽  
Author(s):  
Aistė Beliauskienė ◽  
Skaidra Valiukevičienė ◽  
Brigita Šitkauskienė ◽  
Axel Schnuch ◽  
Wolfgang Uter

Background and Objective. The pattern of contact sensitization among patients with chronic leg ulcers depends on the local practice of wound treatment along with demographic and clinical confounders. The study was aimed at revealing the associations between chronic leg ulcers and contact sensitization. Material and Methods. Between 2006 and 2008, 35 patients with chronic leg ulcers and surrounding dermatitis and 59 patients with contact dermatitis of the lower leg or foot were prospectively recruited at the Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences. Demographic and clinical data were collected in accordance with the “minimal data set” of the European Surveillance System on Contact Allergy. Patch testing was performed with the allergens of the European baseline series. Results. At least one positive patch test reaction was found in 28 (80%) of the patients with chronic leg ulcers and in 24 (41%) of the patients with dermatitis of the lower leg or foot (P<0.001). Sensitization to some of the most common allergens, namely colophony, Myroxylon pereirae resin, and methyldibromo glutaronitrile, was prevalent in both the groups of patients, whereas sensitization to benzocaine, p-phenylenediamine, and lanolin alcohol was associated with the presence of chronic leg ulcers. Benzocaine was found to be the leading allergen among patients with chronic leg ulcers (positive patch test reactions in 34.4% of the patients). Conclusions. Contact sensitization to benzocaine, p-phenylenediamine, and lanolin was found to be associated with the presence of chronic leg ulcers.


2014 ◽  
Vol 23 (1) ◽  
pp. 5-12 ◽  
Author(s):  
F. Jockenhöfer ◽  
H. Gollnick ◽  
Katharina Herberger ◽  
G. Isbary ◽  
R. Renner ◽  
...  

2014 ◽  
Vol 72 (2) ◽  
pp. 90-96 ◽  
Author(s):  
Aude Valois ◽  
Julie Waton ◽  
Martine Avenel-Audran ◽  
François Truchetet ◽  
Evelyne Collet ◽  
...  

Phlebologie ◽  
2009 ◽  
Vol 38 (05) ◽  
pp. 211-218 ◽  
Author(s):  
C. Wax ◽  
A. Körber ◽  
J. Dissemond ◽  
J. Klode

SummaryChronic leg ulcer may have various causes, which are currently not centrally recorded in Germany. It is also unclear who treats patients with chronic leg ulcers in Germany and how the basic implementation of diagnosis and treatment of these patients looks like. Patients, methods: Therefore, we started a survey of 1000 general practitioners and practising specialists in dermatology, surgery and phlebology in five different regions of Germany. We carried out the genesis of a total of 6275 patients from 62 different practising therapists, 33 specialists in dermatology, surgery or phlebology and 29 general practitioners. Results: In 66.1% of all patients we found a venous leg ulcer, in 9.1% a leg ulcer from peripheral arterial occlusive disease, and in 8.5% a mixture of both. Thus there suffered a total of 83.8% of patients on chronic venous insufficiency or peripheral arterial occlusive disease as a major factor in the genesis of the chronic leg ulcer. However, even the rarely diagnosed entities such as exogenous factors, vasculitis, pyoderma gangrenosum or infectious diseases are occur in summation in 16.2% of all patients and should therefore be known and excluded. In addition, the treatment periods and referral routes of patients with chronic leg ulcer should be identified. The analysis showed that the vast majority (86.8%) of patients with chronic ulcers who were investigated by us is treated by specialists. The treatment duration of general practitioners is 6.3 weeks (mean value) before the patient will be referred to a specialist. This treatment period is significantly shorter compared to the treatment period of the specialists, who treat their patients 14.1 weeks (mean value) before the patient will be referred to another specialist or to a clinic. Conclusion: Our results show the current aspects of aetiology and the way of treatment of patients with chronic leg ulcers in Germany.


1997 ◽  
Vol 168 (1) ◽  
pp. 155-157 ◽  
Author(s):  
D Karasick ◽  
M E Schweitzer ◽  
D M Deely

2020 ◽  
Author(s):  
Astrid H. Lossius ◽  
Merete Lorentzen ◽  
Joar Austad ◽  
Tone K. Bergersen

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