Are corpora lutea induced by human chorionic gonadotropin (hCG) given on day 7 of the bovine estrous cycle functional?

1994 ◽  
Vol 41 (1) ◽  
pp. 293
Author(s):  
P.C. Sianangama ◽  
R. Rajamahendran ◽  
C. Harvey-Clark
Endocrinology ◽  
2003 ◽  
Vol 144 (10) ◽  
pp. 4597-4606 ◽  
Author(s):  
Minnie Hsieh ◽  
Sabine M. Mulders ◽  
Robert R. Friis ◽  
Arun Dharmarajan ◽  
JoAnne S. Richards

Secreted frizzled-related protein-4 (sFRP-4) belongs to a family of soluble proteins that have a Frizzled-like cysteine-rich domain and function as modulators of Wnt-Frizzled (Fz) signals. As several Wnts and Fz are expressed at defined stages of follicular development in rodent ovaries, these studies were undertaken to evaluate the hormone-regulated expression and localization of sFRP-4. In the mouse ovary, the expression of sFRP-4 mRNA was up-regulated in granulosa cells of large antral follicles after human chorionic gonadotropin administration and was also elevated in corpora lutea, as determined by RT-PCR and in situ hybridization analyses. In hypophysectomized rat ovaries, sFRP-4 expression was similarly induced by human chorionic gonadotropin and further up-regulated by PRL. PRL also stimulated the secretion of sFRP-4 protein from luteinized rat granulosa cells in culture. Therefore, regulation of sFRP-4 by LH and PRL may be important for modulating Fz-1, which is known to be expressed in periovulatory follicles, and Wnt-4/Fz-4, which are expressed in corpora lutea.


2022 ◽  
Vol 22 (1) ◽  
pp. 100591
Author(s):  
Juliana Nascimento Duarte Rodrigues ◽  
José Domingos Guimarães ◽  
Maria Emilia Franco Oliveira ◽  
Jenniffer Hauschildt Dias ◽  
Aline Matos Arrais ◽  
...  

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