scholarly journals Role of vitamin D in endothelial function and endothelial repair in clinically stable systemic lupus erythematosus

The Lancet ◽  
2015 ◽  
Vol 385 ◽  
pp. S83 ◽  
Author(s):  
John Reynolds ◽  
David Ray ◽  
M Yvonne Alexander ◽  
Ian Bruce
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Endothelial Function ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Endothelial Repair

Role of vitamin D in endothelial repair mechanisms in systemic lupus erythematosus

The Lancet ◽  
2014 ◽  
Vol 383 ◽  
pp. S89 ◽  
Author(s):  
John Reynolds ◽  
David Ray ◽  
Terence O'Neill ◽  
M Yvonne Alexander ◽  
Ian Bruce
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Endothelial Repair ◽  
Repair Mechanisms

scholarly journals Role of Vitamin D in Systemic Lupus Erythematosus

2014 ◽  
Vol 2 (4) ◽  
pp. 662-667 ◽  
Author(s):  
Rada Miskovic ◽  
Aleksandra Plavsic ◽  
Jasna Bolpacic ◽  
Sanvila Raskovic ◽  
Mirjana Bogic
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Lupus Erythematosus ◽  
Animal Studies ◽  
Potential Role ◽  
Vitamin D Supplementation ◽  
Vitamin D Status ◽  
Systemic Lupus

Vitamin D is a steroid hormone that in addition to its well known role in the metabolism of calcium and phosphorus exerts immunoregulatory properties. Data from animal studies and from prospective clinical trials on patients with rheumatoid arthritis, multiple sclerosis and type 1 diabetes point to the potential role of vitamin D as important environmental factor in the development of autoimmune diseases. Such role of vitamin D in systemic lupus erythematosus (SLE) has not yet been sufficiently studied. This review shows the sources, metabolism and mechanism of action of vitamin D, its effect on the cells of the immune system, prevalence and causes of vitamin D deficiency in patients with SLE, the link between vitamin D status and disease activity as well as recommendations for vitamin D supplementation.

scholarly journals THE IMMUNOMODULATORY ROLE OF VITAMIN D IN SYSTEMIC LUPUS ERYTHEMATOSUS: AN INTEGRATING LITERATURE REVIEW

2018 ◽  
Vol 2 (4) ◽  
pp. 88-99
Author(s):  
Lucas Tavares Cruz de Albuquerque ◽  
Caroline Pereira Modesto ◽  
Pedro De Sousa Leite ◽  
Ana Aurélia Tavares da Cruz ◽  
Djailson Ricardo Malheiro
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Lupus Erythematosus ◽  
Inflammatory Markers ◽  
Scientific Literature ◽  
Adequate Intake ◽  
Systemic Lupus ◽  
The Subject

Vitamin D, conceptually, is a pre-hormone. Many studies have shown that the vitamin D deficiency may be associated to a higher incidence of autoimmune diseases, including Systemic Lupus Erythematosus. So, this work’s purpose is identify what the scientific literature approaches about the vitamin D, highlighting its immunomodulatory role with the Systemic Lupus Erythematosus. We used the article survey that ran upon the subject in the Medline, Scielo and Lilacs databases with the descriptors: vitamin D, Systemic Lupus Erythematosus and autoimmune disease. The selected articles pointed out higher prevalence in the vitamin D deficiency and insufficiency in Lupus patients. In these, the supplementation appeared to improve the disease activity and inflammatory markers and shows a tendency for subsequent clinical improvement. However, there is a lack of adequate intake guidelines. In this way, researches about the best dosage of vitamin D are needed for these patients in order to improve their condition.

The beneficial role of vitamin D in systemic lupus erythematosus (SLE)

2012 ◽  
Vol 31 (10) ◽  
pp. 1423-1435 ◽  
Author(s):  
Khanh vinh quốc Lương ◽  
Lan Thi Hoàng Nguyễn
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Beneficial Role

scholarly journals Role of vitamin D deficiency in systemic lupus erythematosus incidence and aggravation

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Tohid Hassanalilou ◽  
Leila Khalili ◽  
Saeid Ghavamzadeh ◽  
Ali Shokri ◽  
Laleh Payahoo ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Lupus Erythematosus ◽  
Systemic Lupus

scholarly journals Study on the Role of Vitamin D in Systemic Lupus Erythematosus

2021 ◽  
Vol 4 (1) ◽  
pp. 23
Author(s):  
Jiadian Wang ◽  
Muzi Cui ◽  
Siyi Wang ◽  
Xiao Xue ◽  
Kerong Ren ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vitamin D ◽  
Lupus Erythematosus ◽  
Biological Effects ◽  
Research Progress ◽  
Target Cells ◽  
Systemic Lupus ◽  
Vitamin D Receptors

Vitamin D is a hormone precursor with multiple biological effects. It binds to vitamin D receptors on target cells. It is an important participant in the metabolism of calcium and phosphorus in vivo. It is closely related to cell cycle, cell proliferation, differentiation, apoptosis, signal transduction and immune regulation. Its role in the treatment of infection, tumor and even immune diseases has been gradually recognized and studied. Patients with systemic lupus erythematosus generally have decreased levels of active vitamin D, and low levels of vitamin D are associated with disease occurrence, disease activity and complications. In the past ten years, a large number of studies have been carried out on it globally to explore the role of vitamin D in the occurrence and development of systemic lupus erythematosus. This paper summarizes its recent research progress.

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