The Use of Botulinum Toxin for Treatment of Acquired Nystagmus and Oscillopsia

Ophthalmology ◽  
1994 ◽  
Vol 101 (4) ◽  
pp. 783-787 ◽  
Author(s):  
Simon T. Ruben ◽  
John P. Lee ◽  
Damian O'Neil ◽  
Iain Dunlop ◽  
John S. Elston
1995 ◽  
Vol 119 (4) ◽  
pp. 489-496 ◽  
Author(s):  
ROBERT L. TOMSAK ◽  
BERND F. REMLER ◽  
LEA AVERBUCH-HELLER ◽  
MOHAN CHANDRAN ◽  
R. JOHN LEIGH

1992 ◽  
Vol 32 (5) ◽  
pp. 633-642 ◽  
Author(s):  
R. John Leigh ◽  
Robert L Tomsak ◽  
Michael P. Grant ◽  
Bernd F. Remler ◽  
Stacy S. Yaniglos ◽  
...  

1994 ◽  
Vol 14 (4) ◽  
pp. 223
Author(s):  
Ruben ST ◽  
Lee JP ◽  
O??Neil D ◽  
Dunlop I ◽  
Elston JS

1996 ◽  
Vol 16 (1) ◽  
pp. 62
Author(s):  
R L Tomsak ◽  
B F Remler ◽  
L Averbuch-Heller ◽  
M Chandran ◽  
R J Leigh

2012 ◽  
Vol 21 (1) ◽  
pp. 15-21
Author(s):  
Merete Bakke ◽  
Allan Bardow ◽  
Eigild Møller

Severe drooling is associated with discomfort and psychosocial problems and may constitute a health risk. A variety of different surgical and non-surgical treatments have been used to diminish drooling, some of them with little or uncertain effect and others more effective but irreversible or with side effects. Based on clinical evidence, injection with botulinum toxin (BTX) into the parotid and submandibular glands is a useful treatment option, because it is local, reversible, and with few side effects, although it has to be repeated. The mechanism of BTX is a local inhibition of acetylcholine release, which diminishes receptor-coupled secretion and results in a flow rate reduction of 25–50% for 2–7 months.


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