Presentation of endogenous acetylcholine receptor (AChR) by human myoblasts to AChR-specific CD4+ T helper cell clones from myasthenia gravis (MG) patients

1998 ◽  
Vol 90 (1) ◽  
pp. 88
Author(s):  
J. Curnow ◽  
L. Corlett ◽  
N. Nagvekar ◽  
N. Willcox ◽  
A. Vincent
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Cell Clones

scholarly journals T helper cell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits.

1993 ◽  
Vol 92 (2) ◽  
pp. 1055-1067 ◽  
Author(s):  
A A Manfredi ◽  
M P Protti ◽  
M W Dalton ◽  
J F Howard ◽  
B M Conti-Tronconi
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
T Helper Cell ◽  
Helper Cell ◽  
Cell Recognition ◽  
T Helper

EFFECT OF CYCLOSPORIN A ON MURINE AND HUMAN T HELPER CELL CLONES

1982 ◽  
Vol 34 (5) ◽  
pp. 308-311 ◽  
Author(s):  
R. K. FIDELUS ◽  
R. M. FERGUSON ◽  
M. B. WIDMER ◽  
S-L. WEE ◽  
F. H. BACH ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Cell Clones

scholarly journals Characterization of rat T helper cell clones specific for Bacteroides gingivalis antigen.

1990 ◽  
Vol 58 (9) ◽  
pp. 2785-2791 ◽  
Author(s):  
J Katz ◽  
S M Michalek ◽  
K W Beagley ◽  
J H Eldridge
Keyword(s):  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Cell Clones ◽  
Bacteroides Gingivalis

Interleukin-9–Induced Expression of M-Ras/R-Ras3 Oncogene in T-Helper Clones

Blood ◽  
1999 ◽  
Vol 94 (5) ◽  
pp. 1701-1710 ◽  
Author(s):  
Jamila Louahed ◽  
Luigi Grasso ◽  
Charles De Smet ◽  
Emiel Van Roost ◽  
Claude Wildmann ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Cell Clone ◽  
T Helper Cell ◽  
Representational Difference Analysis ◽  
Helper Cell ◽  
T Helper ◽  
Ras Gene ◽  
Cell Clones ◽  
Ras Family ◽  
Interleukin 9

In an attempt to gain insight into the molecular mechanisms involved in interleukin-9 (IL-9) activities, representational difference analysis (RDA) was used to identify messages that are induced by IL-9 in a murine T-helper–cell clone. One of the isolated genes encodes for the newly described M-Ras or R-Ras3, which is part of the Ras gene superfamily. M-Ras expression was found to be induced by IL-9 but not IL-2 or IL-4 in various murine T-helper–cell clones, and this induction seems to be dependent on the JAK/STAT pathway. Contrasting with the potent upregulation of M-Ras expression, M-Ras was not activated by IL-9 at the level of guanosine triphosphate/guanosine diphosphate (GTP/GDP) binding. However, IL-3 increased GTP binding to M-Ras, suggesting that M-Ras induction might represent a new mechanism of cooperativity between cytokines such as IL-3 and IL-9. Constitutively activated M-Ras mutants induced activation of Elk transcription factor by triggering the MAP kinase pathway and allowed for IL-3–independent proliferation of BaF3 cells. Taken together, these results show that cytokines such as IL-9 can regulate the expression of a member of the RAS family possibly involved in growth-factor signal transduction.

Myasthenia gravis associated with T helper cell lymphoma

Neurology ◽  
1987 ◽  
Vol 37 (8) ◽  
pp. 1405-1405 ◽  
Author(s):  
J. D. Bowen ◽  
P. Kidd
Keyword(s):  
Myasthenia Gravis ◽  
Cell Lymphoma ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper

A method for generating antigen-specific rat T helper cell clones

1991 ◽  
Vol 138 (1) ◽  
pp. 77-86 ◽  
Author(s):  
Jannet Katz ◽  
Suzanne M. Michalek
Keyword(s):  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Cell Clones
Sign in / Sign up

Export Citation Format

Share Document