The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons

Directed Mutagenesis ◽

Dna Alkyltransferase

Crucial role of the orexin-B C-terminus in the induction of OX1receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis

British Journal of Pharmacology ◽

10.1111/bph.13287 ◽

2015 ◽

Vol 172 (21) ◽

pp. 5211-5223 ◽

Cited By ~ 6

Author(s):

Pascal Nicole ◽

Pierre Couvineau ◽

Nadege Jamin ◽

Thierry Voisin ◽

Alain Couvineau

Keyword(s):

Molecular Modelling ◽

Crucial Role ◽

Directed Mutagenesis ◽

Alanine Scanning ◽

C Terminus

Functional characterization of an anti-estradiol antibody by site-directed mutagenesis and molecular modelling: modulation of binding properties and prominent role of the VLdomain in estradiol recognition

Journal of Molecular Recognition ◽

10.1002/jmr.553 ◽

2002 ◽

Vol 15 (1) ◽

pp. 6-18 ◽

Cited By ~ 7

Author(s):

Stéphane Coulon ◽

Jean-Luc Pellequer ◽

Thierry Blachère ◽

Martine Chartier ◽

Elisabeth Mappus ◽

...

Keyword(s):

Molecular Modelling ◽

Functional Characterization ◽

Directed Mutagenesis ◽

Binding Properties

Site-directed mutagenesis and molecular modelling studies show the role of Asp82 and cysteines in rat acylase 1, a member of the M20 family

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2005.03.019 ◽

2005 ◽

Vol 330 (2) ◽

pp. 540-546

Author(s):

Sameh Herga ◽

Alexandre Brutus ◽

Rosa Maria Vitale ◽

Hélène Miche ◽

Josette Perrier ◽

...

Keyword(s):

Molecular Modelling ◽

Directed Mutagenesis ◽

Molecular Modelling Studies ◽

Modelling Studies

Site-directed mutagenesis of beta-lactamase TEM-1. Investigating the potential role of specific residues on the activity of Pseudomonas-specific enzymes

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1993.tb18324.x ◽

1993 ◽

Vol 217 (3) ◽

pp. 939-946 ◽

Cited By ~ 12

Author(s):

Francise LENFANT ◽

Agnes PETIT ◽

Roger LABIA ◽

Laurent MAVEYRAUD ◽

Jean-Pierre SAMAMA ◽

...

Keyword(s):

Potential Role ◽

Directed Mutagenesis ◽

Beta Lactamase

Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Directed Mutagenesis ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Nadph Cytochrome P450 Reductase

The role of cysteine 206 in allosteric inhibition of Escherichia coli citrate synthase. Studies by chemical modification, site-directed mutagenesis, and 19F NMR.

10.1016/s0021-9258(18)54766-9 ◽

1991 ◽

Vol 266 (31) ◽

pp. 20709-20713

Author(s):

L.J. Donald ◽

B.R. Crane ◽

D.H. Anderson ◽

H.W. Duckworth

Keyword(s):

Escherichia Coli ◽

Chemical Modification ◽

Citrate Synthase ◽

19F Nmr ◽

Directed Mutagenesis ◽

Allosteric Inhibition

Role of Cysteine Residues in the N-Terminal Extracellular Domain of the Human VIP 1 Receptor for Ligand Binding A Site-directed Mutagenesis Studya

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1996.tb17524.x ◽

2006 ◽

Vol 805 (1) ◽

pp. 585-589 ◽

Cited By ~ 4

Author(s):

PASCALE GAUDIN ◽

ALAIN COUVINEAU ◽

JEAN-JOSÉ MAORET ◽

CHRISTIANE ROUYER-FESSARD ◽

MARC LABURTHE

Keyword(s):

Ligand Binding ◽

Extracellular Domain ◽

Cysteine Residues ◽

Directed Mutagenesis ◽

A Site

Site-directed mutagenesis of tyrosine hydroxylase. Role of serine 40 in catalysis.

10.1016/s0021-9258(18)35673-4 ◽

1992 ◽

Vol 267 (36) ◽

pp. 25754-25758

Author(s):

J Wu ◽

D Filer ◽

A.J. Friedhoff ◽

M Goldstein

Keyword(s):

Tyrosine Hydroxylase ◽

Directed Mutagenesis

Determination of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase by site-directed mutagenesis

Zurich, Switzerland, September 3–8, 1989 ◽

10.1515/9783110889000-148 ◽

1990 ◽

pp. 765-768

Keyword(s):

Dihydrofolate Reductase ◽

Functional Role ◽

Directed Mutagenesis ◽

Human Dihydrofolate Reductase

The role of cysteines in polyketide synthases. Site-directed mutagenesis of resveratrol and chalcone synthases, two key enzymes in different plant-specific pathways

10.1016/s0021-9258(18)92914-5 ◽

1991 ◽

Vol 266 (15) ◽

pp. 9971-9976 ◽

Cited By ~ 3

Author(s):

T. Lanz ◽

S. Tropf ◽

F.J. Marner ◽

J. Schröder ◽

G. Schröder

Keyword(s):

Polyketide Synthases ◽

Directed Mutagenesis ◽

Key Enzymes