Maximum likelihood parameter estimation in the three-parameter log-normal distribution using the continuation method

1997 ◽  
Vol 24 (2) ◽  
pp. 139-152 ◽  
Author(s):  
Hideo Hirose
Mathematics ◽  
2021 ◽  
Vol 9 (23) ◽  
pp. 3113
Author(s):  
Muhammed Rasheed Irshad ◽  
Christophe Chesneau ◽  
Soman Latha Nitin ◽  
Damodaran Santhamani Shibu ◽  
Radhakumari Maya

Many studies have underlined the importance of the log-normal distribution in the modeling of phenomena occurring in biology. With this in mind, in this article we offer a new and motivated transformed version of the log-normal distribution, primarily for use with biological data. The hazard rate function, quantile function, and several other significant aspects of the new distribution are investigated. In particular, we show that the hazard rate function has increasing, decreasing, bathtub, and upside-down bathtub shapes. The maximum likelihood and Bayesian techniques are both used to estimate unknown parameters. Based on the proposed distribution, we also present a parametric regression model and a Bayesian regression approach. As an assessment of the longstanding performance, simulation studies based on maximum likelihood and Bayesian techniques of estimation procedures are also conducted. Two real datasets are used to demonstrate the applicability of the new distribution. The efficiency of the third parameter in the new model is tested by utilizing the likelihood ratio test. Furthermore, the parametric bootstrap approach is used to determine the effectiveness of the suggested model for the datasets.


2021 ◽  
Vol 71 (6) ◽  
pp. 1565-1580
Author(s):  
Hugo S. Salinas ◽  
Guillermo Martínez-Flórez ◽  
Artur J. Lemonte ◽  
Heleno Bolfarine

Abstract In this paper, we present a new parametric class of distributions based on the log-alpha-power distribution, which contains the well-known log-normal distribution as a special case. This new family is useful to deal with unimodal as well as bimodal data with asymmetry and kurtosis coefficients ranging far from that expected based on the log-normal distribution. The usual approach is considered to perform inferences, and the traditional maximum likelihood method is employed to estimate the unknown parameters. Monte Carlo simulation results indicate that the maximum likelihood approach is quite effective to estimate the model parameters. We also derive the observed and expected Fisher information matrices. As a byproduct of such study, it is shown that the Fisher information matrix is nonsingular throughout the sample space. Empirical applications of the proposed family of distributions to real data are provided for illustrative purposes.


Biology ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 64
Author(s):  
Arnaud Millet

The mechanosensitivity of cells has recently been identified as a process that could greatly influence a cell’s fate. To understand the interaction between cells and their surrounding extracellular matrix, the characterization of the mechanical properties of natural polymeric gels is needed. Atomic force microscopy (AFM) is one of the leading tools used to characterize mechanically biological tissues. It appears that the elasticity (elastic modulus) values obtained by AFM presents a log-normal distribution. Despite its ubiquity, the log-normal distribution concerning the elastic modulus of biological tissues does not have a clear explanation. In this paper, we propose a physical mechanism based on the weak universality of critical exponents in the percolation process leading to gelation. Following this, we discuss the relevance of this model for mechanical signatures of biological tissues.


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