Modified N-methyl-d-aspartate receptor subunit expression emerges in reeler Purkinje cells after accomplishment of the adult wild-type expression

1996 ◽  
Vol 26 (4) ◽  
pp. 335-343 ◽  
Author(s):  
Masahiko Watanabe ◽  
Irina Maria Moise ◽  
Yoshiro Inoue
Keyword(s):  
Purkinje Cells ◽  
Receptor Subunit ◽  
Wild Type ◽  
Aspartate Receptor ◽  
Subunit Expression

Phencyclidine treatment increases NR2A and NR2B N-methyl-D-aspartate receptor subunit expression in rats

Neuroreport ◽  
2011 ◽  
Vol 22 (17) ◽  
pp. 935-938 ◽  
Author(s):  
Sylwia Owczarek ◽  
Jack Hou ◽  
Thomas Secher ◽  
Lars V. Kristiansen
Keyword(s):  
Receptor Subunit ◽  
Aspartate Receptor ◽  
Subunit Expression

scholarly journals Regulation of N-Methyl-d-Aspartate Receptor Subunit Expression in the Fetal Guinea Pig Brain1

2004 ◽  
Vol 71 (2) ◽  
pp. 676-683 ◽  
Author(s):  
Dawn Owen ◽  
Elaine Setiawan ◽  
Antai Li ◽  
Lucy McCabe ◽  
Stephen G. Matthews
Keyword(s):  
Guinea Pig ◽  
Receptor Subunit ◽  
Aspartate Receptor ◽  
Subunit Expression

scholarly journals Cognitive Impairment That Is Induced by (R)-Ketamine Is Abolished in NMDA GluN2D Receptor Subunit Knockout Mice

2019 ◽  
Vol 22 (7) ◽  
pp. 449-452 ◽  
Author(s):  
Soichiro Ide ◽  
Yuiko Ikekubo ◽  
Masayoshi Mishina ◽  
Kenji Hashimoto ◽  
Kazutaka Ikeda
Keyword(s):  
Cognitive Impairment ◽  
Neural Mechanisms ◽  
Racemic Mixture ◽  
Novel Object Recognition ◽  
The Novel ◽  
Receptor Subunit ◽  
Wild Type ◽  
Object Recognition Test ◽  
Aspartate Receptor ◽  
Antidepressant Effects

AbstractAlthough the N-methyl-D-aspartate receptor antagonist ketamine has attracted attention because of its rapid and sustained antidepressant effects in depressed patients, its side effects have raised some concerns. Ketamine is a racemic mixture of equal amounts of the enantiomers (R)-ketamine and (S)-ketamine. The neural mechanisms that underlie the differential effects of these enantiomers remain unclear. We investigated cognitive impairment that was induced by ketamine and its enantiomers in N-methyl-D-aspartate GluN2D receptor subunit knockout (GluN2D-KO) mice. In the novel object recognition test, (RS)-ketamine and (S)-ketamine caused cognitive impairment in both wild-type and GluN2D-KO mice, whereas (R)-ketamine induced such cognitive impairment only in wild-type mice. The present results suggest that the GluN2D subunit plays an important role in cognitive impairment that is induced by (R)-ketamine, whereas this subunit does not appear to be involved in cognitive impairment that is induced by (RS)-ketamine or (S)-ketamine.

The effect of ketamine on N-methyl-D-aspartate receptor subunit expression in neonatal rats

2010 ◽  
Vol 27 (2) ◽  
pp. 181-186 ◽  
Author(s):  
Li-Chun Han ◽  
Li-nong Yao ◽  
Sheng-xi Wu ◽  
Yong-hui Yang ◽  
Li-Xian Xu ◽  
...  
Keyword(s):  
Receptor Subunit ◽  
Neonatal Rats ◽  
Aspartate Receptor ◽  
Subunit Expression
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