Comparision of two different primer sets for PCR detection of transfusion transmitted virus DNA in blood donors, hemodialysis patients and patients with thalassemia major, chronic HBV and HCV infection

2001 ◽  
Vol 34 (0) ◽  
pp. 163 ◽  
Author(s):  
H Verdi
Keyword(s):  
Blood Donors ◽  
Thalassemia Major ◽  
Hemodialysis Patients ◽  
Pcr Detection ◽  
Hcv Infection ◽  
Transmitted Virus ◽  
Chronic Hbv ◽  
Primer Sets ◽  
Transfusion Transmitted Virus

Molecular Detection of Transfusion Transmitted Virus Coinfection With Some Hepatotropic Viruses

2006 ◽  
Vol 130 (11) ◽  
pp. 1680-1683
Author(s):  
Maysaa El-Sayed Zaki ◽  
Nagy Abd El Hady, MD
Keyword(s):  
Polymerase Chain Reaction ◽  
Viral Hepatitis ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Blood Donors ◽  
Unknown Etiology ◽  
Chain Reaction ◽  
Transmitted Virus ◽  
Polymerase Chain ◽  
Transfusion Transmitted Virus

Abstract Context.—A novel human DNA virus was isolated from the serum of a patient with posttransfusion hepatitis; it was named transfusion transmitted virus (TTV). Objective.—To ascertain the influence of TTV (detected by polymerase chain reaction amplification of a conserved region of the viral genome) coinfection in individuals infected with hepatitis viruses (A, B, and C) and to investigate the putative role played by TTV in hepatic dysfunction in individuals with acute non-A-E hepatitis. Design.—Sixty-two patients with viral hepatitis were included in the study in addition to 18 blood donors. Viral study of 4 hepatotropic viruses (A, B, C, and E) was carried out. Study for TTV DNA was performed by nested polymerase chain reaction. Results.—The prevalence of TTV was not statistically different between hepatitis patients and blood donors, and it was not correlated to the levels of the hepatic aspartate aminotransferase and alanine aminotransferase between individuals evidencing dual infection with hepatitis B and C viruses and healthy blood donors. However, in the group of patients with viral hepatitis of unknown etiology (non-A-E), those evidencing TTV viremia had statistically significant lower levels of alanine aminotransferase (P = .03) and aspartate aminotransferase (P = .04) than those who were TTV negative. Conclusions.—We can conclude that TTV is a frequent virus isolated from patients with various types of viral hepatitis, from cases of hepatitis without obvious viral agent, and from the healthy population. TTV has no effect on biochemical markers of associated viral hepatitis. It may be associated with a mild form of non-A-E hepatitis.

Transfusion‐transmitted virus infection in China: Prevalence in blood donors and in patients with liver diseases

1999 ◽  
Vol 14 (9) ◽  
pp. 899-903 ◽  
Author(s):  
Chuan He ◽  
Fumio Nomura ◽  
Nobuyasu Yukimasa ◽  
Sakae Itoga ◽  
Maki Yamada‐Osaki ◽  
...  
Keyword(s):  
Virus Infection ◽  
Liver Diseases ◽  
Blood Donors ◽  
Transmitted Virus ◽  
Transfusion Transmitted Virus

scholarly journals Higher Frequency of Transfusion-Transmitted Virus (TTV) in HIV Patients in Comparison with Healthy Blood Donors

2017 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mohammad Taheri ◽  
Mohammad Motamedifar ◽  
Jamal Sarvari ◽  
Ramin Yaghoobi ◽  
Negin Nikouyan ◽  
...  
Keyword(s):  
Blood Donors ◽  
Hiv Patients ◽  
Transmitted Virus ◽  
Transfusion Transmitted Virus

Transfusion Transmitted Virüs (TTV) Prevalansı İnaktif Hepatit B Taşıyıcılarında Hemodiyalizden Etkileniyor Mu

2018 ◽  
Vol 28 (2) ◽  
pp. 45-47
Author(s):  
Servet Kölgelier ◽  
Nazlım Aktuğ Demir ◽  
Şua Sümer ◽  
Lütfü Saltuk Demir ◽  
Abdullah Arpacı
Keyword(s):  
Transmitted Virus ◽  
Transfusion Transmitted Virus
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