[123] SUSTAINED VIROLOGICAL RESPONSE RATES WITH PEGINTERFERON a-2a (40 kD) (PEGASYS®) PLUS RIBAVIRIN (COPEGUS®) IN RANDOMISED CONTROLLED CLINICAL TRIALS ARE REPLICATED IN THE CLINICAL PRACTICE SETTING

2007 ◽  
Vol 46 ◽  
pp. S55
Author(s):  
A. Alberti ◽  
E. Zehnter ◽  
S.S. Lee ◽  
S.J. Hadziyannis ◽  
S. Zeuzem ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Clinical Practice ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Response Rates ◽  
Practice Setting ◽  
Controlled Clinical Trials ◽  
Clinical Practice Setting ◽  
Randomised Controlled

Treatment of HCV genotype 2 with sofosbuvir and ribavirin results in lower sustained virological response rates in real life than expected from clinical trials

2016 ◽  
Vol 37 (2) ◽  
pp. 205-211 ◽  
Author(s):  
Frank Tacke ◽  
Rainer Günther ◽  
Peter Buggisch ◽  
Hartwig Klinker ◽  
Andreas Schober ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Real Life ◽  
Response Rates ◽  
Hcv Genotype ◽  
Genotype 2 ◽  
Hcv Genotype 2

scholarly journals Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting

2014 ◽  
Vol 15 (14) ◽  
pp. 1739-1747 ◽  
Author(s):  
Otito F Iwuchukwu ◽  
QiPing Feng ◽  
Wei-Qi Wei ◽  
Lan Jiang ◽  
Min Jiang ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Clinical Practice ◽  
Practice Setting ◽  
Clinical Practice Setting

Trends in randomized controlled trials in ENT: a 30-year review

1997 ◽  
Vol 111 (7) ◽  
pp. 611-613 ◽  
Author(s):  
K. W. Ah-See ◽  
N. C. Molony ◽  
A. G. D. Maran
Keyword(s):  
Clinical Trials ◽  
Clinical Practice ◽  
Randomized Controlled Trials ◽  
Gold Standard ◽  
Controlled Trials ◽  
Evidence Based ◽  
Controlled Clinical Trials ◽  
Medline Search ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled

AbstractThere is a growth in the demand for clinical practice to be evidence based. Recent years have seen a rise in the number of randomized controlled clinical trials (RCTS). Such trials while acknowledged as the gold standard for evidence can be difficult to perform in surgical specialities. We have recently identified a low proportion of RCTS in the otolaryngology literature. Our aim was to identify any trend in the number of published RCTS within the ENT literature over a 30-year period and to identify which areas of our speciality lend themselves to this form of study design. A Medline search of 10 prominent journals published between 1966 and 1995 was performed. Two hundred and ninety-six RCTS were identified. Only five were published before 1980. Two hundred (71 per cent) of RCTS were in the areas of otology and rhinology. An encouraging trend is seen in RCTS within ENT literature.

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