Evidence of Recent Hepatitis E Virus Infection in Portuguese Blood Donors

2016 ◽  
Vol 64 (2) ◽  
pp. S460
Author(s):  
J. Abreu-Silva ◽  
S.S. Pereira ◽  
J. Teixeira ◽  
R.M.S. Oliveira ◽  
J. Tomaz ◽  
...  
Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 492
Author(s):  
Magdalena Baymakova ◽  
Krasimira Terzieva ◽  
Rumen Popov ◽  
Elisaveta Grancharova ◽  
Todor Kundurzhiev ◽  
...  

Hepatitis E virus (HEV) infection is widespread among domestic pigs, industrial swine, and wild boars in Bulgaria. The aim of the current research was to present the HEV seroprevalence among blood donors in Bulgaria. In the present study, 555 blood donors (479 males and 76 females) were enrolled from five districts in the country (Shumen, Pleven, Stara Zagora, Plovdiv, and Sofia districts). All blood samples were tested for anti-HEV IgG using the recomWell HEV IgG ELISA test (Mikrogen GmbH, Neuried, Germany). Each participating donor completed a short, structured, and specific questionnaire to document data on the current study. Anti-HEV IgG positive results were detected in 144 (25.9%) blood donors, including 129 (26.9%) males and 15 (19.7%) females. The established HEV seropositivity was 28.8% (23/80) in Shumen district, 23.2% (22/95) in Pleven district, 27.1% (38/140) in Stara Zagora district, 27.5% (44/160) in Plovdiv district, and 21.3% (17/80) in Sofia district. A high HEV seroprevalence was found for persons who declared that they were general hunters (48.7%; 19/39; p = 0.001) and hunters of wild boars (51.6%; 16/31; p = 0.001). We present the first seroprevalence rates of HEV infection in blood donors from Bulgaria. The results of our research showed high HEV seropositivity among blood donors.


Transfusion ◽  
2018 ◽  
Vol 59 (3) ◽  
pp. 1035-1043 ◽  
Author(s):  
Duangnapa Intharasongkroh ◽  
Thanunrat Thongmee ◽  
Pattaratida Sa-nguanmoo ◽  
Sirapa Klinfueng ◽  
Ausanee Duang-in ◽  
...  

Transfusion ◽  
2013 ◽  
Vol 54 (1) ◽  
pp. 49-56 ◽  
Author(s):  
David Juhl ◽  
Sally A. Baylis ◽  
Johannes Blümel ◽  
Siegfried Görg ◽  
Holger Hennig

Transfusion ◽  
2016 ◽  
Vol 57 (2) ◽  
pp. 248-257 ◽  
Author(s):  
Longmu Zhang ◽  
Shuxian Jiao ◽  
Zhongsi Yang ◽  
Lei Xu ◽  
Li Liu ◽  
...  

Author(s):  
Cinzia Marcantonio ◽  
Patrizio Pezzotti ◽  
Roberto Bruni ◽  
Gloria Taliani ◽  
Paola Chionne ◽  
...  

2012 ◽  
Vol 50 (8) ◽  
pp. 2708-2713 ◽  
Author(s):  
T. Vollmer ◽  
J. Diekmann ◽  
R. Johne ◽  
M. Eberhardt ◽  
C. Knabbe ◽  
...  

2009 ◽  
Vol 4 (n2) ◽  
pp. 299-301 ◽  
Author(s):  
H. Ikeda ◽  
K. Matsubayashi ◽  
H. Sakata ◽  
H. Takeda ◽  
S. Sato ◽  
...  

2013 ◽  
Vol 18 (31) ◽  
Author(s):  
E Slot ◽  
B M Hogema ◽  
A Riezebos-Brilman ◽  
T M Kok ◽  
M Molier ◽  
...  

In Europe, the dynamics of endemic hepatitis E virus (HEV) infection remain enigmatic. We studied the presence of silent HEV infection among Dutch blood donors. Using donations collected throughout the Netherlands in 2011 and 2012, 40,176 donations were tested for HEV RNA in 459 pools of 48 or 480 donations. Deconstruction of the reactive pools identified 13 viraemic donors. In addition, 5,239 donors were tested for presence of anti-HEV IgG and IgM and for HEV RNA when IgM-positive. Of the 5,239 donations, 1,401 (27%) tested repeat-positive for HEV IgG, of which 49 (3.5%) also tested positive for anti-HEV IgM. Four of the HEV IgM-positive donors tested positive for HEV RNA. HEV IgG seroprevalence ranged from 13% among donors younger than 30 years to 43% in donors older than 60 years. The finding of 17 HEV RNA-positive donations among 45,415 donations corresponds to one HEV-positive blood donation per day in the Netherlands. For 16 of the 17 HEV RNA-positive donors, genotyping succeeded, revealing HEV genotype 3, which is circulating among Dutch pigs. Apparently, silent HEV infection is common in the Netherlands, which possibly applies to larger parts of Europe.


2019 ◽  
Vol 33 (3) ◽  
pp. 139-145 ◽  
Author(s):  
Gilles Delage ◽  
Margaret Fearon ◽  
Yves Gregoire ◽  
Boris M Hogema ◽  
Brian Custer ◽  
...  

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