Lung carcinoid tumours: analysis of changes in follow-up protocol in a single UK centre

Lung Cancer ◽  
2021 ◽  
Vol 156 ◽  
pp. S4-S5
Author(s):  
Devan Limbachia ◽  
Helen Weaver ◽  
Mohammad Hawari
2008 ◽  
Vol 123 (7) ◽  
pp. 789-792 ◽  
Author(s):  
T Galm ◽  
N Turner

AbstractObjective:We present the first reported case of primary carcinoid tumour of the nasal septum.Method:Case report of our experience of a carcinoid tumour of the nasal septum. We discuss our clinical, radiological and pathological findings.Result:An 83-year-old woman presented with a history of left-sided nasal blockage. Clinical examination showed a unilateral, left-sided nasal polyp. Further imaging and histological analysis confirmed this to be a carcinoid tumour. Carcinoid tumours outside the gastrointestinal tract are rare. There have been reports of carcinoid tumours in the head and neck region, but no published cases occurring in the nasal septum. Our management involved wide surgical resection with regular follow up to monitor for recurrence and for the development of carcinoid syndrome. Four years from initial presentation, the patient remained free of the primary tumour and had displayed no signs or symptoms suggestive of carcinoid syndrome.Conclusion:To the authors' best knowledge, and after searching the world literature, the presented case represents the first report of primary carcinoid tumour of the nasal septum. Despite its rarity, this tumour should be considered as part of the differential diagnosis, as timely recognition and intervention are critical for successful treatment.


Lung Cancer ◽  
2019 ◽  
Vol 127 ◽  
pp. S63-S64
Author(s):  
M. Mccloskey ◽  
C. Yarr ◽  
K. Grant ◽  
M. Doherty ◽  
R. Sharkey ◽  
...  

2017 ◽  
Vol 6 (3) ◽  
pp. 387-392 ◽  
Author(s):  
Henal Motiwala ◽  
Itisha Bansal ◽  
Pradeep Goyal ◽  
Olena Dorokhova ◽  
Yogesh Kumar ◽  
...  
Keyword(s):  

Author(s):  
Dragan R. Subotic ◽  
Nikola Atanasijadis ◽  
Vladimir Milenkovic ◽  
Milan Savic ◽  
Dejan Moskovljevic ◽  
...  

2007 ◽  
Vol 43 (18) ◽  
pp. 2651-2657 ◽  
Author(s):  
Anouk N.A. van der Horst-Schrivers ◽  
Wendy J. Post ◽  
Ido P. Kema ◽  
Thera P. Links ◽  
Pax H.B. Willemse ◽  
...  

Author(s):  
Cornelis JM Lips ◽  
Eef GWM Lentjes ◽  
Jo WM Höppener

Carcinoids are neuroendocrine tumours of the gut which may also be found in the bronchus, pancreatic islets and retroperitoneum. They probably arise from gastrointestinal or bronchopulmonary pluripotential stem cells. Carcinoid tumours derived from these cells are potentially malignant; the strength of the tendency for aggressive growth correlates with the site of origin, depth of local penetration and the size of the tumour. Carcinoids occur sporadically or result from specific hereditary tumour syndromes. Mutations and/or aberrant expression of specific genes induce and promote tumour growth. Clinical features include local symptoms due to angulation or obstruction and hepatomegaly due to liver metastases. The carcinoid syndrome commonly involves flushing, diarrhoea, bronchospasm and hypotension. Other distinct syndromes may be caused by tumour release of products that may also be used as biochemical markers in diagnosis and follow-up. Scanning using radiolabelled octreotide, an analogue of somatostatin, sensitively identifies occult primary and metastatic deposits. Localized carcinoid tumours should be resected. Some patients benefit from hepatic resection. Palliation of symptoms is best achieved with octreotide. Hepatic artery chemoembolization may produce long-acting palliation. Further genetic characterization of the different types and stages of carcinoid development as well as assessment of gene expression profiles may improve differential diagnosis, prognosis and treatment.


2011 ◽  
Vol 07 (03) ◽  
pp. 196 ◽  
Author(s):  
Giovanna Rizzardi ◽  
Luca Bertolaccini ◽  
Alberto Terzi ◽  
◽  
◽  
...  

Bronchial carcinoids (BCs) are rare, well-differentiated malignant neuroendocrine tumours that account for 2–5 % of all lung neoplasms in adults. In paediatric patients, carcinoids represent the most frequent primary lung cancer. Although BCs in childhood often have an endobronchial location causing airway obstruction, they are frequently misdiagnosed as benign conditions, resulting in a delay in definitive diagnosis and treatment. Surgery represents the treatment of choice for BCs, and lung-sparing resections (sleeve or bronchoplastic procedures) are recommended in central carcinoid tumours; pneumonectomy should be avoided, particularly in childhood. If promptly diagnosed and radically treated, BCs in children have an excellent prognosis. Relapses can occur many years after a radical resection, highlighting the necessity for long-term follow-up.


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