Polymerase chain reaction diagnosis of enterovirus in children with aseptic meningitis

1999 ◽  
Vol 34 (4) ◽  
pp. S9-S10
Author(s):  
RA Silverman
2021 ◽  
Vol 59 (241) ◽  
pp. 916-918
Author(s):  
Swati Chand ◽  
Sangharsha Thapa ◽  
Khusal Gautam ◽  
Anu Radha Twayana ◽  
Maryrose R.Laguio-Vila ◽  
...  

Mollaret’s meningitis is an aseptic recurrent benign lymphocytic meningitis lasting 2-5 days and occurs over years with spontaneous complete resolution of symptoms between episodes. An 88 years-old-male presented with acute onset headache, lethargy and altered sensorium after a recent ear infection. He had multiple similar episodes in the past, each preceded by ear or sinus infection with cerebrospinal fluid finding consistent with aseptic meningitis. However, no specific causative agent was ever identified. He was confused, disoriented and lethargic with normal vitals and systemic examination. Blood tests showed leukocytosis with neutrophilia. Cerebrospinal fluid analysis revealed increased cell count with lymphocyte predominance, elevated protein and negative polymerase chain reaction. Magnetic resonance imaging of brain showed chronic small vessel ischemic changes. He fulfilled the Bruyn’s criteria for clinical diagnosis. He was empirically administered acyclovir during hospitalization and was discharged without prophylactic antiviraldue to negative cerebrospinal fluid analysis, culture, and multiplex polymerase chain reaction.


2010 ◽  
Vol 105 (8) ◽  
pp. 988-992 ◽  
Author(s):  
Eliete Caló Romero ◽  
Roberta Morozetti Blanco ◽  
Paulo Hideki Yasuda

2016 ◽  
Vol 31 (1) ◽  
pp. 29-31
Author(s):  
Marieke Brauer ◽  
Marianne Wolfaardt ◽  
Lynne M. Webber ◽  
Maureen B. Taylor

The study aimed to determine the presence of mumps virus (MuV) in cerebrospinal fluid (CSF) specimens and to genetically characterise detected MuV strains. A real-time reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the MuV F gene, and characterisation was performed by sequencing of the SH gene. Mumps virus was detected in 1.2% (3/260) of specimens. Phylogenetic analysis of one MuV strain revealed that it clustered with the Jeryl-Lynn and RIT4385 vaccine strains. As far as the authors could ascertain this is the first study to provide viral proof that these vaccine-like strains may be associated with aseptic meningitis.


1992 ◽  
Vol 38 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Martin Glimåker ◽  
Almaz Abebe ◽  
Bo Johansson ◽  
Anneka Ehrnst ◽  
Per Olcén ◽  
...  

Author(s):  
Miriam H. Riding ◽  
Jane Stewart ◽  
Geoffrey B. Clements ◽  
Daniel N. Galbraith

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